Results 1 to 10 of about 105,578,950 (193)

Alpha 2-antiplasmin deficiency in a Sudanese child: a case report [PDF]

Journal of Medical Case Reports, 2021
Background The plasma serine protease inhibitor alpha 2-antiplasmin (α2-AP, otherwise known as α2-plasmin inhibitor) is a rapid-acting plasmin inhibitor recently found in human plasma, which seems to have a significant role in the regulation of in vivo ...
Bashir Abdrhman Bashir Mohammed
doaj   +5 more sources

Generation and characterization of monoclonal antibodies against the N-terminus of alpha-2-antiplasmin. [PDF]

PLoS ONE, 2018
Around 70% of circulating alpha-2-antiplasmin (α2AP), the main natural plasmin inhibitor, is N-terminally cleaved between residues Pro12 and Asn13 by antiplasmin-cleaving enzyme.
Shiraazkhan Abdul, Miet Peeters, Els Brouwers, Joyce J M C Malfliet, Frank W G Leebeek, Paul J Declerck, Dingeman C Rijken, Shirley Uitte de Willige   +7 more
doaj   +4 more sources

Serum Apolipoprotein A-II and Alpha-2-Antiplasmin Levels in Midtrimester Can Be Used as Predictors of Preterm Delivery [PDF]

Journal of International Medical Research, 2020
Objective To identify serum protein markers in midtrimester that predict preterm delivery. Methods A retrospective case–control study randomly selected patients that experienced spontaneous preterm birth and healthy control patients that experienced a ...
Jianxia Huang, Pei He
exaly   +3 more sources

Evaluation of Fibrinolytic Inhibitors: Alpha-2-Antiplasmin and Plasminogen Activator Inhibitor 1 in Patients with Obstructive Sleep Apnoea. [PDF]

PLoS ONE, 2016
Obstructive sleep apnoea (OSA) induces thrombophilia and reduces fibrinolysis. Alpha-2-antiplasmin (a-2-AP) and plasminogen activator inhibitor 1 (PAI-1) are major inhibitors of the fibrinolytic system.
Maciej Zakrzewski, Ewelina Zakrzewska, Paweł Kiciński, Sylwia Przybylska-Kuć, Andrzej Dybała, Wojciech Myśliński, Jolanta Pastryk, Tomasz Tomaszewski, Jerzy Mosiewicz   +8 more
doaj   +2 more sources

Rapid plasma-based screening of fibrinolytic activation in trauma: a single-center observational cohort study [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Viscoelastic testing is commonly used to assess fibrinolytic phenotypes in trauma, with values of thromboelastogram (TEG) clot lysis at 30 minutes after maximum amplitude (LY30) >3% considered indicative of hyperfibrinolysis.
Anton Ilich, Izabela Pawlinski, Matthew J. Eckert, Linda E. Sousse, Jared R. Gallaher, Myung S. Park, Alyssa Caldwell-McGee, Mitchell J. Cohen, Jessica C. Cardenas, Nigel S. Key   +9 more
doaj   +2 more sources

Enhanced thrombin and plasmin generation profiles in alpha-2-antiplasmin–deficient patients: Data from the Rare Bleeding disorders in the Netherlands study [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: α2-Antiplasmin (A2AP) deficiency is a rare and often unidentified disorder characterized by increased fibrinolysis and subsequent bleeding. Global hemostasis assays may increase insight into the altered coagulation and fibrinolysis in these ...
Bauke Haisma, Sanna R. Rijpma, Marjon H. Cnossen, Paul L. den Exter, Ilmar C. Kruis, Karina Meijer, Laurens Nieuwenhuizen, Nick van Es, Roger E.G. Schutgens, Nicole M.A. Blijlevens, Waander L. van Heerde, Saskia E.M. Schols   +11 more
doaj   +2 more sources

Proteomic Mediators of Chronic Obstructive Pulmonary Disease Phenotypes and Coronary Artery Calcification Burden in Ever Smokers [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Chronic obstructive pulmonary disease (COPD) increases cardiovascular disease risk. Coronary artery calcification (CAC) predicts cardiovascular events and mortality in COPD.
Asghar Abbasi, Khadije Ahmad, Katherine A. Pratte, Jeff Moore, Dawn L. DeMeo, Venkat S. Manubolu, April Kinninger, Nicholas B. Tiller, Russell P. Bowler, Mathew Budoff, Richard Casaburi, Harry B. Rossiter   +11 more
doaj   +2 more sources

Coping Styles and Defense Mechanisms in Healthy Young Adults—Correlations with tPA-BDNF Pathway [PDF]

Brain Sciences
Background/Objectives: An increasing number of studies are exploring how stress influences the development of various psychiatric and physical disorders. Psychological coping strategies and defense mechanisms play a vital role in managing stress. However,
Julia Pilecka, Jedrzej Wojciechowski, Weronika Bargiel, Maria Terczynska, Przemyslaw Zakowicz, Dawid Bojarski, Karolina Wasicka-Przewozna, Maria Skibinska   +7 more
doaj   +2 more sources

On the Localization of the Cleavage Site in Human Alpha-2-Antiplasmin, Involved in the Generation of the Non-Plasminogen Binding Form [PDF]

Journal of Thrombosis and Haemostasis, 2020
Frank Leebeek, Dick H W Dekkers, Shirley Uitte de Willige   +2 more
exaly   +2 more sources

Influence of riboflavin and ultraviolet-light treatment on plasma proteins – protein S and alpha 2-antiplasmin – in relation to the time of administration [PDF]

Vojnosanitetski Pregled, 2022
Background/Aim. After the introduction of a careful selection procedure for blood donors and the implementation of highly sensitive screening tests for transfusion-transmitted infections (TTIs), blood has become a very safe product concerning TTIs ...
Gojkov Dragana, Balint Bela, Dejanović Bratislav, Vučetić Dušan   +3 more
doaj   +1 more source