Results 21 to 30 of about 105,578,950 (193)

Acute and chronic blood serum proteome changes in patients with methanol poisoning

Scientific Reports, 2022
Twenty-four blood serum samples from patients with acute methanol poisoning (M) from the mass methanol poisoning outbreak in the Czech Republic in 2012 were compared with 46 patient samples taken four years after poisoning (S) (overlap of 10 people with ...
Pavel Cejnar, Tatiana Anatolievna Smirnova, Stepanka Kuckova, Ales Prochazka, Ivan Zak, Karel Harant, Sergey Zakharov   +6 more
doaj   +1 more source

Hyperbaric Oxygen Inhibits Reperfusion-Induced Neutrophil Polarization and Adhesion Via Plasmin-Mediated VEGF Release

Plastic and Reconstructive Surgery, Global Open, 2017
Background:. Ischemia-reperfusion (IR) injury is seen in many settings such as free flap salvage and limb replantation/revascularization. The consequences—partial/total flap loss, functional muscle loss, or amputation—can be devastating. Of the treatment
Ashish Francis, MD, Shawna R. Kleban, MD, Linda L. Stephenson, BS, Patrick S. Murphy, MD, Peter R. Letourneau, MD, Xin-Hua Fang, MT, Wei Z. Wang, MD, Richard C. Baynosa, MD   +7 more
doaj   +1 more source

Dysregulation of Biomarkers of Hemostatic Activation and Inflammatory Processes are Associated with Adverse Outcomes in Pulmonary Embolism

Clinical and Applied Thrombosis/Hemostasis, 2022
Introduction The pathophysiology of pulmonary embolism (PE) represents complex, multifactorial processes involving blood cells, vascular endothelium, and the activation of inflammatory pathways.
Iman Darwish B.S., Jawed Fareed PhD, Yevgeniy Brailovsky D.O., Debra Hoppensteadt PhD, Brett Slajus M.P.H., Emily Bontekoe B.S., Frank De Stefano B.S., Trent Reed D.O., Amir Darki MSc., M.D.   +8 more
doaj   +1 more source

The plasmin-antiplasmin system: structural and functional aspects [PDF]

, 2010
The plasmin-antiplasmin system plays a key role in blood coagulation and fibrinolysis. Plasmin and (2)-antiplasmin are primarily responsible for a controlled and regulated dissolution of the fibrin polymers into soluble fragments.
Johann Schaller, Gerber, Simon S, Schaller, Johann, Simon S. Gerber, Gerber SS, Schaller J   +5 more
core   +2 more sources

Identification by whole genome sequencing of genes associated with delayed postoperative hemorrhage in Scottish deerhounds

Journal of Veterinary Internal Medicine, 2023
Background Delayed postoperative hemorrhage (DEPOH) is an important health concern for Scottish deerhounds. Hypothesis/Objectives Identify genes associated with DEPOH in Scottish deerhounds.
Michael H. Court, Jennifer N. Kiser, Holly L. Neibergs, Zhaohui Zhu, John E. Dillberger   +4 more
doaj   +1 more source

Fibrinolytic Status and Risk of Death After Acute Pulmonary Embolism

Clinical and Applied Thrombosis/Hemostasis, 2023
Background Acute pulmonary embolism (PE) is a heterogeneous disease process with variable presentation and outcomes. The endogenous fibrinolytic system is a complex framework of regulatory pathways that maintains homeostasis by dissolving overabundant ...
Yevgeniy Brailovsky DO, MSc, Vladimir Lakhter DO, Joshua Newman MD, Sorcha Allen MBBCh, Ahmed Elkaryoni MD, Parth Desai MD, Dalila Masic PharmD, Carlos F. Bechara MD, Emily Bontekoe BS, Debra Hoppensteadt PhD, John J. Lopez MD, Fakiha Siddiqui BDS, Omer Iqbal PhD, Jawed Fareed PhD, Amir Darki, MD, MSc   +14 more
doaj   +1 more source

The impact of rapid infusers on the hemostatic potential of cryoprecipitate products. [PDF]

Transfusion
Abstract Background In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with ...
Purvis CD, Redden S, Jacobson A, Wang YW, Campbell J, Cardenas J, Van Gent JM, Cotton BA.   +7 more
europepmc   +2 more sources

X-ray crystal structure of the fibrinolysis inhibitor {alpha}2-antiplasmin (2R9Y)

, 2016
The serpin alpha(2)-antiplasmin (SERPINF2) is the principal inhibitor of plasmin and inhibits fibrinolysis. Accordingly, alpha(2)-antiplasmin deficiency in humans results in uncontrolled fibrinolysis and a bleeding disorder.
Ruby Law (2569576), James Whisstock (2569573)   +1 more
core   +1 more source

Natural heterogeneity of alpha 2-antiplasmin: functional and clinical consequences

, 2016
Human alpha 2-antiplasmin (alpha 2AP, also called alpha 2-plasmin inhibitor) is the main physiological inhibitor of the fibrinolytic enzyme plasmin.
Rijken, Dick, Uitte de Willige, Shirley, Leebeek, Frank; id_orcid, Abdul, Shiraaz   +3 more
core   +1 more source

The concentration of alpha-2-antiplasmin and plasminogen activator 1 in plasma of patients with obstructive sleep apnoea and the control group.

, 2016
The concentration of alpha-2-antiplasmin and plasminogen activator 1 in plasma of patients with obstructive sleep apnoea and the control group.
Jolanta Pastryk (3353465), Tomasz Tomaszewski (3353474), Sylwia Przybylska-Kuć (3353480), Paweł Kiciński (3353483), Jerzy Mosiewicz (2187583), Maciej Zakrzewski (3353468), Andrzej Dybała (3353486), Wojciech Myśliński (3353477), Ewelina Zakrzewska (3353471)   +8 more
core   +1 more source