Results 31 to 40 of about 105,578,950 (193)

Plasma fibrin clots of pulmonary embolism patients present increased amounts of factor XIII and alpha2-antiplasmin at 3 months' anticoagulation since the acute phase [PDF]

, 2020
Fibrin cross-linking by coagulation factor (F)XIII leads to clot stabilization. Reduced plasma FXIII levels have been reported in acute pulmonary embolism (PE) patients.
Bryk, Agata, Zeitl, K., Wisniewski, J., Sarkady, F., Bryk, A., Undas, A., Zettl, K., Wisniewski, Jacek, Natorska, J., Bagoly, Z., Katona, E., Katona, Eva, Bagoly, Zsuzsa, Barath, Barbara, Zabczyk, M., Natorska, Joanna, Ząbczyk, Michał, Undas, Anetta, Barath, B.   +18 more
core   +1 more source

The alpha-2-antiplasmin and plasminogen activator inhibitor 1 concentrations in the plasma of patients with OSA in relation to selected risk factors of cardiovascular diseases.

, 2016
The alpha-2-antiplasmin and plasminogen activator inhibitor 1 concentrations in the plasma of patients with OSA in relation to selected risk factors of cardiovascular diseases.
Jolanta Pastryk (3353465), Tomasz Tomaszewski (3353474), Sylwia Przybylska-Kuć (3353480), Paweł Kiciński (3353483), Jerzy Mosiewicz (2187583), Maciej Zakrzewski (3353468), Andrzej Dybała (3353486), Wojciech Myśliński (3353477), Ewelina Zakrzewska (3353471)   +8 more
core   +1 more source

The mutual relationship between the two molecular forms of the major fibrinolysis inhibitor alpha-2-antiplasmin in blood

, 1986
Alpha-2-antiplasmin, a major inhibitor of fibrinolysis, is synthesized in the liver and occurs in blood in two molecular forms: a very active plasminogen-binding (PB) form and a less active nonplasminogen-binding (NPB) form.
Kluft, C., Jie, A.F.H., Los, P.
core   +2 more sources

Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent

, 2009
OBJECTIVES: We aimed to investigate whether early thrombus formation can be visualized with in vivo magnetic resonance imaging (MRI) by the use of a novel bimodal alpha(2)-antiplasmin-based contrast agent (CA).
Kooi, M.E., Prinzen, L., Dirksen, A., Herias, M.V., Hackeng, T.M., Miserus, R.J.H.M., Lobbes, M.B.I., Zandvoort, van, M., van Engelshoven, J.M., Heemskerk, J.W., Lobbes, M.B., Daemen, M.J.A.P., van Suylen, R.J., Engelshoven, van, J.M.A., Suylen, Van, R.-J., Heeneman, S., Heemskerk, J.W.M., van Zandvoort, M.A.M.J., Hackeng, T.M.; id_orcid, Miserus, R.J.   +19 more
core   +2 more sources

Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez, Karoline Lantzsch, Romain Topalian, Nadine Gunder, Philipp Hubel, Katharina Schindowski, Jens Pfannstiel, Thomas Hummel   +7 more
wiley   +1 more source

The reactive site of human alpha 2-antiplasmin.

Journal of Biological Chemistry, 1987
Human alpha 2-antiplasmin rapidly forms a stable, equimolar complex with either its target enzyme, plasmin, or with trypsin. Perturbation of the inhibitor-trypsin complex results in peptide bond cleavage at the reactive site of the inhibitor with the concomitant release of a small peptide fragment which apparently represents the carboxyl-terminal ...
B H, Shieh, J, Travis
openaire   +2 more sources

Human Protein Biomarkers Outperform Bacterial Proteins in Colorectal Cancer Detection

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) generally develops from precancerous adenomatous lesions, including advanced adenomas (AA), through a sequence of carcinogenic molecular alterations. The composition of the gut microbiota and the fecal proteome is known to differ between individuals with AA and CRC compared to controls, providing opportunities for ...
Roza C. M. Opperman, Sofie Bosch, Alex A. Henneman, Thang V. Pham, Sander R. Piersma, Tim G. J. de Meij, Meike de Wit, Beatriz Carvalho, Remond J. A. Fijneman, Gerrit A. Meijer, Evelien Dekker, Connie R. Jimenez, Nanne K. H. de Boer   +12 more
wiley   +1 more source

Amino-Terminal Fusion of Epidermal Growth Factor 4,5,6 Domains of Human Thrombomodulin on Streptokinase Confers Anti-Reocclusion Characteristics along with Plasmin-Mediated Clot Specificity.

PLoS ONE, 2016
Streptokinase (SK) is a potent clot dissolver but lacks fibrin clot specificity as it activates human plasminogen (HPG) into human plasmin (HPN) throughout the system leading to increased risk of bleeding.
Neeraj Maheshwari, Satish Kantipudi, Anand Maheshwari, Kashika Arora, Vandana, Neha Kwatra, Girish Sahni   +6 more
doaj   +1 more source

Individual levels of plasma alpha 2-antiplasmin and alpha 2-macroglobulin during the normal menstrual cycle and in women on oral contraceptives low in oestrogen

, 1983
Determinations of alpha 2-antiplasmin and alpha 2-macroglobulin were made in plasma samples collected during one normal or hormone induced cycle in 15 normal women and 11 women using oral contraceptives containing 30 micrograms ethinyl oestradiol and 150
Jespersen, J; id_orcid, Sidelmann, Johannes Jakobsen   +1 more
core   +1 more source

Genetically Disparate Fayoumi Chicken Lines Show Different Response to Avian Necrotic Enteritis

The Journal of Poultry Science, 2015
Necrotic enteritis (NE) has reemerged as a significant problem as a result of growing restrictions of antibiotics in agricultural animal production and increasing concerns over antibiotic resistance in human pathogens.
Duk K. Kim, Hyun S. Lillehoj, Seung I. Jang, Sung H. Lee, Yeong H. Hong, Susan J. Lamont   +5 more
doaj   +1 more source