Results 41 to 50 of about 18,078,412 (185)
Natural heterogeneity of alpha 2-antiplasmin: functional and clinical consequences
, 2016 Human alpha 2-antiplasmin (alpha 2AP, also called alpha 2-plasmin inhibitor) is the main physiological inhibitor of the fibrinolytic enzyme plasmin.
Rijken, Dick +4 more
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Advanced Functional Materials, Volume 36, Issue 37, 7 May 2026.This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal +9 more
wiley +1 more source
A bleeding disorder due to deficiency of alpha 2-antiplasmin. [PDF]
Journal of Clinical Pathology, 1985 The investigation of a 33 year old man with a lifelong bleeding tendency is described. Defective fibrinolysis was suspected in 1968, when clinical bleeding was corrected by administration of aminocaproic acid. The paper establishes the diagnosis as alpha 2-antiplasmin deficiency and describes its management with oral tranexamic acid.
P, Kettle, E E, Mayne
openaire +2 more sources
JGH Open, Volume 10, Issue 5, May 2026.ABSTRACT Thrombocytopenia and leukopenia are among the most common hematological abnormalities in patients with chronic liver disease (CLD), particularly among those with cirrhosis. Thrombocytopenia and leukopenia are associated with increased risks of bleeding, infection, treatment delay, and poor clinical outcomes.
Xiaoxiao Wang +3 more
wiley +1 more source
, 1983 Determinations of alpha 2-antiplasmin and alpha 2-macroglobulin were made in plasma samples collected during one normal or hormone induced cycle in 15 normal women and 11 women using oral contraceptives containing 30 micrograms ethinyl oestradiol and 150
Jespersen, J; id_orcid +1 more
core +1 more source
Aging Cell, Volume 25, Issue 5, May 2026.A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins +8 more
wiley +1 more source
Journal of Biological Chemistry, 1993 Although the plasminogen activating equimolar complex of staphylokinase (STA) with human plasmin is very rapidly inhibited by alpha 2-antiplasmin, STA is a potent fibrinolytic agent in a human plasma milieu which contains 1 microM alpha 2-antiplasmin.
K, Silence, D, Collen, H R, Lijnen
openaire +2 more sources
Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy
Transfusion, Volume 66, Issue S1, Page S246-S256, May 2026.Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna +7 more
wiley +1 more source
, 2016 The alpha-2-antiplasmin and plasminogen activator inhibitor 1 concentrations in the plasma of patients with OSA in relation to selected risk factors of cardiovascular diseases.
Jolanta Pastryk (3353465) +8 more
core +1 more source
, 2016 The concentration of alpha-2-antiplasmin and plasminogen activator 1 in plasma of patients with obstructive sleep apnoea and the control group.
Jolanta Pastryk (3353465) +8 more
core +1 more source