Proteolyzed Variant of IgG with Free C-Terminal Lysine as a Biomarker of Prostate Cancer
Biology, 2021 The differential diagnosis of prostate cancer is problematic due to the lack of markers with high diagnostic accuracy. We previously demonstrated the increased binding of IgG to human plasminogen (PLG) in plasma of patients with prostate cancer (PC ...
Anna Lokshin +10 more
doaj +1 more source
POLYCLONAL ANTIBODIES AGAINST HUMAN PLASMINOGEN KRINGLE 5 [PDF]
, 2017 The aim of the research was to obtain the polyclonal antibodies against a fragment of human plasminogen kringle 5 and to study their immunochemical properties.
Kapustianenko L. G.
core +1 more source
Laureates of the Palladin Prize of the National Academy of Sciences of Ukraine (1985–1986) [PDF]
The Ukrainian Biochemical Journal, 2013 The article presents the information about the life and scientific activity of the Palladin Prize laureats. In 1985, S. O. Kudinov was awarded the Prize for his monograph ”Ca2+ transport systems in nerve cells”. In 1986, A. Ya. Rozanov, A.
R. P. Vynogradova, V. M. Danilova
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Human plasma-derived plasminogen replacement in type 1 plasminogen deficiency: a pediatric case with multisystemic manifestation [PDF]
The article by D€onmez-Demir et al., ‘Novel plasminogen gene mutations in Turkish patients with type I plasminogen deficiency’, recently published in Blood Coagulation and Fibrinolysis[1], was read with great interest. The study’s authors expanded the
Ünal, Ekrem +6 more
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Exposure of plasminogen and the novel plasminogen receptor, Plg-RKT, on activated human and murine platelets [PDF]
, 2020 Plasminogen activation rates are enhanced by cell surface binding. We have previously demonstrated that exogenous plasminogen binds to phosphatidylserine-exposing and spread platelets.
Miles, Lindsey A. +14 more
core +1 more source
Pathogens, 2022 Bacterial acquisition of metals from a host is an essential attribute to facilitate survival and colonization within an infected organism. Staphylococcus aureus, a bacterial pathogen of medical importance, has evolved its strategies to acquire multiple ...
Natália Salazar +5 more
doaj +1 more source
Heat-Treatments Affect Protease Activities and Peptide Profiles of Ruminants' Milk
Frontiers in Nutrition, 2021 Proteases present in milk are heat-sensitive, and their activities increase or decrease depending on the intensity of the thermal treatment applied. The thermal effects on the protease activity are well-known for bovine milk but poorly understood for ...
Juliana A. S. Leite +14 more
doaj +1 more source
S100A10, a novel biomarker in pancreatic ductal adenocarcinoma
Molecular Oncology, 2018 Pancreatic cancer is arguably the deadliest cancer type. The efficacy of current therapies is often hindered by the inability to predict patient outcome.
Moamen Bydoun +8 more
doaj +1 more source
Study of the sites of plasminogen molecule which are responsible for inhibitory effect of Lys-plasminogen on platelet aggregation [PDF]
, 2014 Plasminogen/plasmin system is involved in such important processes as thrombosis, inflammation and cancer. Plasmin and plasminogen mediate their action through plasminogen-binding proteins on the cell surface.
Zhernossekov, D.D. +9 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source