Results 21 to 30 of about 213,256 (305)

Plasminogen-Loaded Fibrin Scaffold as Drug Delivery System for Wound Healing Applications

open access: yesPharmaceutics, 2022
Plasminogen is a protein involved in intravascular and extravascular fibrinolysis, as well as in wound healing, cell migration, tissue formation and angiogenesis.
Tamer Al Kayal   +5 more
doaj   +1 more source

DnaK Functions as a Moonlighting Protein on the Surface of Mycoplasma hyorhinis Cells

open access: yesFrontiers in Microbiology, 2022
Mycoplasma hyorhinis is a common pathogen of swine and is also associated with various human tumors. It causes systemic inflammation, typically polyserositis and polyarthritis, in some infected pigs. However, the pathogenic mechanism of M.
Yao Li   +25 more
doaj   +1 more source

The Deleterious Effects of Impaired Fibrinolysis on Skeletal Development Are Dependent on Fibrin(ogen), but Independent of Interlukin-6

open access: yesFrontiers in Cardiovascular Medicine, 2021
Chronic diseases in growing children, such as autoimmune disorders, obesity, and cancer, are hallmarked by musculoskeletal growth disturbances and osteoporosis.
Heather A. Cole   +22 more
doaj   +1 more source

Hemostasis protein-coding genes, peripheral hemostasis parameters, and atherothrombosis predisposition in patients with cardiovascular disease

open access: yesКардиоваскулярная терапия и профилактика, 2011
Aim. To study the associations between polymorphic variants of hemostasis protein-coding genes, hemostasis system functioning, and atherothrombosis development in patients with cardiovascular disease (CVD). Material and methods.
G. I. Lifshits   +4 more
doaj   +1 more source

Synthesis of human plasminogen by the liver [PDF]

open access: yes, 1980
Genetic types of plasminogen were determined from a donor and a recipient before and after hepatic homotransplantation. Examination of the plasminogen types demonstrated that the liver is the principal site of synthesis of human plasminogen.
Alper, CA   +5 more
core   +1 more source

Plasminogen Receptors and Fibrinolysis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The ability of cells to promote plasminogen activation on their surfaces is now well recognized, and several distinct cell surface proteins have been demonstrated to function as plasminogen receptors. Here, we review studies demonstrating that plasminogen bound to cells, in addition to plasminogen directly bound to fibrin, plays a major role in ...
Lindsey A. Miles   +5 more
openaire   +3 more sources

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

open access: yes, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila   +5 more
core   +2 more sources

Plasminogen activator inhibitors [PDF]

open access: yesBlood, 1987
Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
Sprengers, E.D., Kluft, C.
openaire   +4 more sources

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

open access: yesHepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou   +15 more
wiley   +1 more source

PAI1 blocks NMDA receptor-mediated effects of tissue-type plasminogen activator on cell signaling and physiology [PDF]

open access: yes, 2018
The fibrinolysis proteinase tissue-type plasminogen activator (tPA, also known as PLAT) triggers cell signaling and regulates cell physiology. In PC12 cells, Schwann cells and macrophages, the N-methyl-D-aspartate receptor (NMDA-R) mediates tPA signaling.
Azmoon, Pardis   +5 more
core   +2 more sources

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