Results 11 to 20 of about 136,149 (288)

Plasminogen Receptors and Fibrinolysis [PDF]

International Journal of Molecular Sciences, 2021
The ability of cells to promote plasminogen activation on their surfaces is now well recognized, and several distinct cell surface proteins have been demonstrated to function as plasminogen receptors.
Lindsey A Miles, Malgorzata Wilczynska, Yue Shen   +2 more
exaly   +5 more sources

Cell-dependent antithrombotic effect of tranexamic acid [PDF]

Frontiers in Immunology
BackgroundTranexamic acid (TXA) is a synthetic lysine analog that inhibits fibrinolysis by blocking lysine-binding sites on plasminogen and plasmin. Although early therapeutic TXA reduces bleeding mortality in major trials, prophylactic benefit appears ...
Kata Balog Virág, Kata Balog Virág, Petra Csikós, Petra Csikós, Alexandra Raska, Alexandra Raska, Barbara Baráth, Barbara Baráth, Kristóf Molnár, Natalia Nikolova, Natalia Nikolova, Kiril Tenekedjiev, Kiril Tenekedjiev, Krasimir Kolev, Nikolett Wohner, Nikolett Wohner   +15 more
doaj   +2 more sources

Plasmin–Plasminogen System and Milk Physicochemical Traits in Intensively Reared Chios and Frizarta Ewes: Effects of Lactation Stage, Age, and Somatic Cell Count [PDF]

Animals
The objective of the present study is to evaluate the effects of lactation stage, age, somatic cell count (SCC), and daily milk yield on plasmin–plasminogen (PL–PG) system activity and physicochemical milk traits in intensively reared Chios and Frizarta ...
Aphrodite I. Kalogianni, Eleni Dalaka, Georgios Theodorou, Ioannis Politis, Athanasios I. Gelasakis   +4 more
doaj   +2 more sources

Plasminogen deficiency

Journal of Thrombosis and Thrombolysis, 2017
Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Congenital plasminogen deficiency is a rare autosomal recessive disorder that leads to the development of thick, wood-like ...
Celkan, Tiraje
core   +3 more sources

Differences and Compatibility between Human and Porcine Fibrinolytic Components toward Plasmin Generation and Fibrin Degradation [PDF]

TH Open
Paul Y. Kim, Chengliang Wu, Hena Noorzada, Ali Aftabjahani   +3 more
doaj   +2 more sources

A multifunctional enolase mediates cytoadhesion and interaction with host plasminogen and fibronectin in Mycoplasma hyorhinis

Veterinary Research, 2022
Mycoplasma hyorhinis may cause systemic inflammation of pigs, typically polyserositis and arthritis, and is also associated with several types of human cancer. However, the pathogenesis of M.
Jia Wang, Yanfei Yu, Yao Li, Shiyang Li, Li Wang, Yanna Wei, Yuzi Wu, Bala Pillay, Ademola Olufolahan Olaniran, Thamsanqa E. Chiliza, Guoqing Shao, Zhixin Feng, Qiyan Xiong   +12 more
doaj   +1 more source

Phosphorylation of human plasminogen activators and plasminogen [PDF]

FEBS Letters, 1995
Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio, DE PETRO, Giuseppina, BONA C, PARACINI F, TONELLI M.   +4 more
openaire   +3 more sources

C-Terminal Lysine Residue of Pneumococcal Triosephosphate Isomerase Contributes to Its Binding to Host Plasminogen

Microorganisms, 2023
The main causative agent of pneumonia, Streptococcus pneumoniae, is also responsible for invasive diseases. S. pneumoniae recruits human plasminogen for the invasion and colonization of host tissues. We previously discovered that S.
Satoru Hirayama, Takumi Hiyoshi, Yoshihito Yasui, Hisanori Domon, Yutaka Terao   +4 more
doaj   +1 more source

Surface Protein Dispersin of Enteroaggregative Escherichia coli Binds Plasminogen That Is Converted Into Active Plasmin

Frontiers in Microbiology, 2020
Dispersin is a 10.2 kDa-immunogenic protein secreted by enteroaggregative Escherichia coli (EAEC). In the prototypical EAEC strain 042, dispersin is non-covalently bound to the outer membrane, assisting dispersion across the intestinal mucosa by ...
Claudia T. P. Moraes, Jonathan Longo, Ludmila B. Silva, Daniel C. Pimenta, Eneas Carvalho, Mariana S. L. C. Morone, Nancy da Rós, Solange M. T. Serrano, Ana Carolina M. Santos, Roxane M. F. Piazza, Angela S. Barbosa, Waldir P. Elias   +11 more
doaj   +1 more source

MHJ_0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae [PDF]

Open Biology, 2013
Bacterial aminopeptidases play important roles in pathogenesis by providing a source of amino acids from exogenous proteins, destroying host immunological effector peptides and executing posttranslational modification of bacterial and host proteins.
Mark W. Robinson, Kyle A. Buchtmann, Cheryl Jenkins, Jessica L. Tacchi, Benjamin B. A. Raymond, Joyce To, Piklu Roy Chowdhury, Lauren K. Woolley, Maurizio Labbate, Lynne Turnbull, Cynthia B. Whitchurch, Matthew P. Padula, Steven P. Djordjevic   +12 more
doaj   +1 more source