Results 11 to 20 of about 136,538 (301)
Journal of Thrombosis and Thrombolysis, 2016 Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Congenital plasminogen deficiency is a rare autosomal recessive disorder that leads to the development of thick, wood-like pseudomembranes on mucosal surfaces, mostly seen in conjunctivas named as ''ligneous conjunctivitis ...
Celkan, Tiraje
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Phosphorylation of human plasminogen activators and plasminogen [PDF]
FEBS Letters, 1995 Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio +4 more
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Plasminogen-derived peptide promotes adipogenic differentiation of preadipocytes in vitro and in vivo [PDF]
, 2022 Soft tissue defects caused by adipose tissue loss can result in various conditions such as lipodystrophy in congenital diseases, trauma secondary to aging, and mastectomy in breast cancer; fat grafting is commonly performed to restore these defects ...
Jong-Ho Kim (317877) +3 more
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Frontiers in Molecular Biosciences, 2023 Accelerated activation of the human plasminogen zymogen (hPg) to two-chain active plasmin (hPm) is achieved following conformational changes induced by ligand-binding at the lysine-binding sites (LBSs) in four of the five hPg kringle domains.
Yetunde A. Ayinuola +2 more
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The Annexin A2/S100A10 Complex: The Mutualistic Symbiosis of Two Distinct Proteins
Biomolecules, 2021 Mutualistic symbiosis refers to the symbiotic relationship between individuals of different species in which both individuals benefit from the association.
Alamelu Bharadwaj +2 more
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Molecules, 2021 Fungi fibrinolytic compound 1 (FGFC1) is a rare marine-derived compound that can enhance fibrinolysis both in vitro and in vivo. The fibrinolytic activity characterization of FGFC1 mediated by plasminogen (Glu-/Lys-) and a single-chain urokinase-type ...
Chunli Gao +8 more
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Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
, 2003 Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +9 more
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Effect of dsRNA on Mesangial Cell Synthesis of Plasminogen Activator Inhibitor Type 1 and Tissue Plasminogen Activator [PDF]
, 2009 Background/Aims: Viral infections are a major problem worldwide and many of them are complicated by virally induced glomerulonephritides. Progression of kidney disease to renal failure is mainly attributed to the development of renal fibrosis ...
Wörnle, Markus +4 more
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Structural basis for the pathophysiology of lipoprotein(a) in the athero-thrombotic process
Brazilian Journal of Medical and Biological Research, 1997 Lipoprotein Lp(a) is a major and independent genetic risk factor for atherosclerosis and cardiovascular disease. The essential difference between Lp(a) and low density lipoproteins (LDL) is apolipoprotein apo(a), a glycoprotein structurally similar to ...
E. Anglés-Cano
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Plasminogen–receptor KT: plasminogen activation and beyond [PDF]
Journal of Thrombosis and Haemostasis, 2017 The cell surface orchestrates plasminogen activation through the concomitant binding of plasminogen and plasminogen activators to specific receptors. In this issue, Miles and colleagues describe their detailed phenotypic characterization of mice deficient in Plg-RKT, a key plasminogen receptor expressed in numerous tissues, but highly expressed by ...
M J, Flick, T H, Bugge
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