Results 21 to 30 of about 150,656 (304)
Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Cucchiara, B. +8 more
core +1 more source
Tissue Plasminogen Activator in Psoriasis
Elevated levels of the serine proteinase plasminogen activator are observed in psoriatic lesions. In contrast to normal epidermis, lesional psoriatic epidermis contains primarily tissue type plasminogen activator (tPA) activity and much lower levels of urokinase type plasminogen activator (uPA) activity.
Jensen, P. J. +6 more
openaire +3 more sources
Tissue plasminogen activator mRNA in murine tissues [PDF]
The urokinase‐type and tissue‐type plasminogen activators are the two enzymes found in mammals, which specifically convert the zymogen plasminogen to plasmin. Using cDNA probes, we have assayed for the presence of the two types of plasminogen activator mRNAs in murine tissues.
Rickles, Richard J., Strickland, Sidney
openaire +2 more sources
Introduction: Few published reports highlight intravenous tissue plasminogen activator use during the first trimester of pregnancy and provide outcomes for mother and fetus.
Gary D Peksa, Jamie Ostrem, Teresa Davis
doaj +1 more source
Successful Treatment of Arterial Thrombus in an Extremely Low-Birth-Weight Preterm Neonate
Arterial thromboembolism in the pediatric population frequently occurs secondary to arterial catheterization. Catheterization-related complications are more common in smaller and sicker infants, due to high prothrombotic activity, low levels of natural ...
Petek G. Kayıran +2 more
doaj +1 more source
Orolingual angioedema is a rare, but extremely dangerous complication of systemic thrombolytic therapy with recombinant tissue plasminogen activator, the incidence of which reaches 2.2-5.1 %.
E. A. Kovaleva +6 more
doaj +1 more source
Tumor markers in breast cancer - European Group on Tumor Markers recommendations [PDF]
Recommendations are presented for the routine clinical use of serum and tissue-based markers in the diagnosis and management of patients with breast cancer.
Abraha RS +136 more
core +1 more source
Prothrombinase Components Can Accelerate Tissue Plasminogen Activator-catalyzed Plasminogen Activation [PDF]
The enzymatic and cofactor subunits of human prothrombinase, factor Xa (FXa) and factor Va (FVa), respectively, were evaluated as modulators of Glu- and Lys-plasminogen (Pg) activation by tissue plasminogen activator (tPA). The data revealed that both FXa and FVa could accelerate tPA activity by as much as 60-fold for Lys-Pg and > 150-fold for Glu-Pg ...
E L, Pryzdial, L, Bajzár, M E, Nesheim
openaire +2 more sources
Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and, as a result, aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage.
Justyna Rajewska-Tabor +5 more
doaj +1 more source
A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams +158 more
core +1 more source

