Results 151 to 160 of about 57,547 (311)

The temporal and embodied structure of the mineness sphere: some phenomenological ideas to frame mental health. [PDF]

Front Psychol
Sánchez CS.
europepmc   +1 more source

Disaffiliation from Jewish Ultra-Orthodox Communities: Life Trajectories Shaped by the Axes of Rigidity-Fluidity and Alterity-Inclusion. [PDF]

Contemp Jew, 2022
Velan B, Tawil Y, Marciano A, Truzman T.
europepmc   +1 more source

The Space Between Us; Taking Stock, Looking Ahead [PDF]

The attempt to theorise certain concepts like “the region†or "spatial development" should begin with the conceptualisation of the very basic element of them that is space.
Vasilis Avdikos
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Haptic Aesthetics as the Possibility of Haptic Epistemology

ESPES
The denotative and theoretical indeterminacy make the sense of touch an ambiguous concept to work with. While materiality and relationality, traditionally assigned in philosophical discourses and acknowledged through scientific research, are considered ...
Maša Tomšič
doaj  

Potent antioxidant and mitochondrial-protective effects of ATH434, a moderate affinity iron chaperone. [PDF]

J Biol Chem
Bailey DK, Nihlawi R, Bradbury MJ, Bond S, Kosman DJ.   +4 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

"Hell is other people". Schizophrenia and urbanicity in the light of predictive coding theory. [PDF]

Front Psychiatry
Mosca A, Pettorruso M, Martinotti G.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Correction: Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson's disease: pooled analysis of patient level data from two randomized open-label studies. [PDF]

J Neurol
Ferreira JJ, Lee JY, Ma HI, Jeon B, Poewe W, Antonini A, Stocchi F, Rodrigues DM, Fonseca MM, Castilla-Fernández G, Holenz J, Rocha JF, Rascol O, ADOPTION study investigators.   +13 more
europepmc   +1 more source