Results 111 to 120 of about 350,171 (307)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Multiband Slot-Based Dual Composite Right/Left-Handed Transmission Line

open access: yesAdvanced Electromagnetics, 2012
A dual Composite Right-/Left-Handed Transmission Line (CRLH TL) implementation that presents multiband behaviour is proposed in this contribution. The artificial TL is realized by loading a host microstrip line with alternate rectangular stubs and slots.
E. Abdo-Sanchez   +2 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Arbuscular mycorrhizal fungi as mediators of ecosystem responses to nitrogen deposition: A trait-based predictive framework [PDF]

open access: yes, 2018
Anthropogenic nitrogen (N) deposition is exposing plants and their arbuscular mycorrhizal fungi (AMFs) to elevated N availability, often leading to shifts in communities of AMF.
Allen, EB   +6 more
core   +1 more source

ALTERNATIVE HOSTS OF Alternaria cucumerina

open access: yes, 2009
A mancha ou queima de alternaria em cucurbitáceas é causada pelo fungo Alternaria cucumerina. Esta doença é uma das mais severas em solos arenosos e causa danos devido ao desfolhamento que predispõe os frutos à queimadura do sol, além de redução no tamanho e qualidade dos mesmos.
Batista, Patrício Ferreira   +4 more
openaire   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Malaria parasites: the great escape

open access: yesFrontiers in Immunology, 2016
Parasites of the genus Plasmodium have a complex life cycle. They alternate between their final mosquito host and their intermediate hosts. The parasite can be either extra- or intracellular, depending on the stage of development.
Laurent Rénia, Yun Shan Goh
doaj   +1 more source

Host-Range Evolution: Adaptation and Trade-Offs in Fitness of Mites on Alternative Hosts [PDF]

open access: yesEcology, 2000
Trade-offs in fitness on different host plants has been a central hypothesis in explaining the evolutionary specialization of herbivores. Surprisingly, only a few studies have documented such trade-offs. In this paper, I present results from a selection experiment that demonstrates trade-offs in host plant use for a polyphagous spider mite.
openaire   +1 more source

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