Results 61 to 70 of about 646,532 (282)

Algebraic functions with even monodromy

, 2003
Let $X$ be a compact Riemann surface of genus $g$ and $d\geq 12g+4$ be an integer. We show that $X$ admits meromorphic functions with monodromy group equal to the alternating group $A_d.
Artebani, Michela, Pirola, Gian Pietro
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

On the lattice of pronormal subgroups of dicyclic, alternating and symmetric groups [PDF]

Mathematica Bohemica
In this paper, the structures of collection of pronormal subgroups of dicyclic, symmetric and alternating groups $G$ are studied in respect of formation of lattices ${\rm L}(G)$ and sublattices of ${\rm L}(G)$.
Shrawani Mitkari, Vilas Kharat
doaj   +1 more source

Noncommutative Riemannian Geometry of the Alternating Group A_4

, 2001
We study the noncommutative Riemannian geometry of the alternating group $A_4=(Z_2 \times Z_2)\cross Z_3$ using a recent formulation for finite groups.
Bresser, D. Lambert, Dimakis, F. Ngakeu, Majid, Majid, S. Majid, Sitarz, Woronowicz   +8 more
core   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Non-inclusive diagnosability of alternating group network

AKCE International Journal of Graphs and Combinatorics
In order to study the fault-tolerant capability of the multiprocessor system, several new self-diagnosis fault-tolerant models are proposed. In particular, non-inclusive diagnosability was showed by Ding et.al. in 2020.
Yalan Li, Yulin Han
doaj   +1 more source

Bimanual coordination deficits in hands following stroke and their relationship with motor and functional performance

Journal of NeuroEngineering and Rehabilitation, 2019
Background Stroke can lead to movement disorders that affect interlimb coordination control of the bilateral upper extremities, especially the hands. However, few studies have investigated the influence of a stroke on bimanual force coordination control ...
Chien-Hung Lai, Wen-Hsu Sung, Shang-Lin Chiang, Liang-Hsuan Lu, Chia-Huei Lin, Yi-Chun Tung, Chueh-Ho Lin   +6 more
doaj   +1 more source

Experimental Study on Mechanical Deformation Characteristics of Inclined and Straight Alternating Pile Groups

Advances in Civil Engineering, 2020
In order to investigate the bearing characteristics of inclined straight alternating pile groups under vertical and horizontal loads, the indoor model test of 2 × 2 inclined straight alternating pile groups with two layers of soil on low pile caps was ...
Desen Kong, Meixu Deng, Yazhou Li
doaj   +1 more source

Maximal irredundant families of minimal size in the alternating group

, 2019
Let $G$ be a finite group. A family $\mathcal{M}$ of maximal subgroups of $G$ is called `irredundant' if its intersection is not equal to the intersection of any proper subfamily.
Garonzi, Martino, Lucchini, Andrea
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source