Results 41 to 50 of about 151,737 (266)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Binary permutation groups: Alternating and classical groups [PDF]
American Journal of Mathematics, 2020 We introduce a new approach to the study of finite binary permutation groups and, as an application of our method, we prove Cherlin's binary groups conjecture for groups with socle a finite alternating group, and for the $\mathcal{C}_1$-primitive actions of the finite classical groups.
Gill, N, Spiga, P
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Generators for Alternating and Symmetric Groups [PDF]
Journal of the Australian Mathematical Society, 1971 Let Γ denote the modular group, that is, the free product of a group of order 2 and a group of order 3. Morris Newman investigates in [2] the factor-groups of Γ and calls them Γ-groups for short; thus a group is a Γ-group if and only if it has a generating set consisting of an element of order dividing 2 and an element of order dividing 3.
Dey, I. M. S., Wiegold, J.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Animals, 2021 The aim of the present study was to assess the effects of a prolonged photoperiod on growth rate and sexual maturation in brook trout Salvelinus fontinalis.
Katsiaryna Lundova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Invariance groups of finite functions and orbit equivalence of permutation groups
Open Mathematics, 2015 Which subgroups of the symmetric group Sn arise as invariance groups of n-variable functions defined on a k-element domain? It appears that the higher the difference n-k, the more difficult it is to answer this question.
Horváth Eszter K. +3 more
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Mathematics, 2020 The structure of the commutator subgroup of Sylow 2-subgroups of an alternating group A 2 k is determined. This work continues the previous investigations of me, where minimal generating sets for Sylow 2-subgroups of alternating groups were ...
Ruslan V. Skuratovskii
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ON THE CHARACTERISATION OF ALTERNATING GROUPS BY CODEGREES
Bulletin of the Australian Mathematical SocietyAbstractLet G be a finite group and $\mathrm {Irr}(G)$ the set of all irreducible complex characters of G. Define the codegree of $\chi \in \mathrm {Irr}(G)$ as $\mathrm {cod}(\chi ):={|G:\mathrm {ker}(\chi ) |}/{\chi (1)}$ and let $\mathrm {cod}(G):=\{\mathrm {cod}(\chi ) \mid \chi \in \mathrm {Irr}(G)\}$ be the codegree set of G.
MALLORY DOLORFINO +4 more
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