Results 41 to 50 of about 1,992,211 (291)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Proximal Alternating Direction Method with Relaxed Proximal Parameters for the Least Squares Covariance Adjustment Problem

open access: yesAbstract and Applied Analysis, 2014
We consider the problem of seeking a symmetric positive semidefinite matrix in a closed convex set to approximate a given matrix. This problem may arise in several areas of numerical linear algebra or come from finance industry or statistics and thus has
Minghua Xu   +3 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin   +14 more
wiley   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi   +10 more
wiley   +1 more source

Optimal policy for multi-alternative decisions

open access: yesNature Neuroscience, 2019
Abstract Every-day decisions frequently require choosing among multiple alternatives. Yet, the optimal policy for such decisions is unknown. Here we derive the normative policy for general multi-alternative decisions. This strategy requires evidence accumulation to nonlinear, time-dependent bounds, that trigger choices.
Satohiro Tajima   +3 more
openaire   +5 more sources

Endotrivial modules for the symmetric and alternating groups. [PDF]

open access: yes, 2009
In this paper we determine the group of endotrivial modules for certain symmetric and alternating groups in characteristic $p$. If $p=2$, then the group is generated by the class of $\Omega^n(k)$ except in a few low degrees.
Mazza, Nadia   +2 more
core   +4 more sources

Distributed Active-Passive Reconfigurable Intelligent Surface Assisted MISO Secure Communications

open access: yesIEEE Access
This paper addresses the secure communication problem in a distributed active-passive reconfigurable intelligent surface (RIS) assisted multiple-input single-output (MISO) scenario with a single-antenna malicious eavesdropper.
Yi Peng   +5 more
doaj   +1 more source

Intelligent Reflecting Surface-Assisted Secure Multi-Input Single-Output Cognitive Radio Transmission

open access: yesSensors, 2020
Intelligent reflecting surface (IRS) is a very promising technology for the development of beyond 5G or 6G wireless communications due to its low complexity, intelligence, and green energy-efficient properties.
Haitao Xiao, Limeng Dong, Wenjie Wang
doaj   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth   +6 more
wiley   +1 more source

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