Results 31 to 40 of about 167,440,407 (273)

2,3,7,8-tetrachlorodibenzo-p-dioxin induces multigenerational testicular toxicity and biosynthetic disorder of testosterone in BALB/C mice: Transcriptional, histopathological and hormonal determinants

open access: yesEcotoxicology and Environmental Safety, 2023
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a potent environmental contaminant, is an endocrine disrupter with a proven reproductive toxicity in mammals. However, its effects on male fertility across generations are still elusive.
Walaa Faiad   +2 more
doaj   +1 more source

Generic alternatives in general practice. [PDF]

open access: yesBMJ, 1984
Using a standard analysis of one month's prescribing in a general practice we showed a potential saving of 8.8% (pounds 883.22) of the net cost of ingredients through substituting exact generic alternatives. Our results confirm the possible reduction in cost of drugs to the National Health Service by the use of generic substitution as suggested in the ...
R J, Anderson, P M, Reilly
openaire   +2 more sources

Generalization of right alternative rings [PDF]

open access: yesTransactions of the American Mathematical Society, 1975
We study nonassociative rings R R satisfying the conditions (1)
Hentzel, Irvin Roy   +1 more
openaire   +2 more sources

Survival of Kamchatka pink salmon as result of combined influence of density regulation and environmental factors

open access: yesИзвестия ТИНРО, 2015
Dynamics of stock abundance and survival is similar for the pink salmon populations from East Kamchatka and West Kamchatka, obviously because of the same large-scale environmental factors influence, as the Pacific Decadal Oscillation (PDO) and the ...
Mark G. Feldman, Eugeny A. Shevlyakov
doaj   +1 more source

Cancer cells exhibit clonal diversity in phenotypic plasticity [PDF]

open access: yesOpen Biology, 2017
Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain ...
Robert Austin Mathis   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Rapid turnover of life-cycle-related genes in the brown algae

open access: yesGenome Biology, 2019
Background Sexual life cycles in eukaryotes involve a cyclic alternation between haploid and diploid phases. While most animals possess a diploid life cycle, many plants and algae alternate between multicellular haploid (gametophyte) and diploid ...
Agnieszka P. Lipinska   +6 more
doaj   +1 more source

ALTERNATION OF GENERATIONS

open access: yesAnnals of Botany, 1898
n ...
openaire   +2 more sources

ALTERNATION OF GENERATIONS IN THE ARCHEGONIATAE

open access: yesAnnals of Botany, 1898
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy