Results 51 to 60 of about 3,709 (253)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Russian symbolism on social aesthetics
RUDN journal of Sociology, 2020 This article is a review of the book Literature and Religious-Philosophical Thought of the Late 19th - First Third of the 20th Century. To the 165th anniversary of V.S. Solovyov (Book 2. E.A. Takho-Godi (Ed.).
M. L. Ivleva, D. D. Romanov
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Generating functions and generalized alternating subsets
Discrete Mathematics, 1975 The notion of an alternating subset of integers is generalized to the notion of an ( , )-alternating subset of integers, where and are arbitrary positive integers. The problem of enumerating the ( , 1)-alternating k-subsets of {1 2, , n} is solved by means of a generating function approach related to the multisections of series.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Genomic methylation patterns in pre-meiotic gynoecia of wild-type and RdDM mutants of Arabidopsis
Frontiers in Plant Science, 2023 IntroductionAlthough DNA methylation patterns are generally considered to be faithfully inherited in Arabidopsis thaliana (Arabidopsis), there is evidence of reprogramming during both male and female gametogenesis.
Quetzely Ortiz-Vasquez +8 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
DEVELOPMENT OF INNOVATIONS IN A TRANSPORT AND LOGISTIC COMPLEX
Модернизация, инновация, развитие, 2015 In article the analysis of rates of alternation of generations of equipment and technologies in separate elements of a transport and logistic complex is given.
A. I. Fedorenko
doaj
On reproduction in red algae: further research needed at the molecular level
Frontiers in Plant Science, 2015 Multicellular red algae (Rhodophyta) have some of the most complex life cycles known in living organisms. Economically valuable seaweeds, such as phycocolloid producers, have a triphasic (gametophyte, carposporophyte and tetrasporophyte) life cycle, not ...
Pilar eGarcía-Jiménez +1 more
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Generators for Alternating and Symmetric Groups [PDF]
Journal of the Australian Mathematical Society, 1971 Let Γ denote the modular group, that is, the free product of a group of order 2 and a group of order 3. Morris Newman investigates in [2] the factor-groups of Γ and calls them Γ-groups for short; thus a group is a Γ-group if and only if it has a generating set consisting of an element of order dividing 2 and an element of order dividing 3.
Dey, I. M. S., Wiegold, J.
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