Results 141 to 150 of about 1,179,365 (340)
Properties of glycans that activate the human alternative complement pathway and interact with the human monocyte beta-glucan receptor. [PDF]
, 1985 J K Czop, K. Frank Austen
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Mean-semivariance behavior (II): The D-CAPM [PDF]
For over 30 years academics and practitioners have been debating the merits of the CAPM. One of the characteristics of this model is that it measures risk by beta, which follows from an equilibrium in which investors display mean-variance behavior.
Estrada, Javier
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Alternative Methods of the Beta Coefficient Estimation [PDF]
International Journal of Trade, Economics and Finance, 2016 T. Kliestik, E. Spuchlakova
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Alternating Copolymers of beta-Alkoxystyrenes and N-Phenylmaleimide
Croatica Chemica Acta, 1987 Alternating copolymers of beta-alkoxystyrenes (I) and N phenylmaleimide (NPMI) were prepared by free-radical initiated polymerization in bulk or in toluene as solvent. The equilibrium constants of I (R = Et and sec-Bu) and NPMI were determined by the transformed Benessi-Hildebrand NMR method in CDC13, and it was found that the bulkiness of alkyl group ...
Vuković, R., Kurešević, V., Fleš, D.
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Alternatives for beet (Beta vulgaris L.) leaves revalorization
, 2020 Red beet plants (Beta vulgaris L.) are widely cultivated for the consumption of their roots, generating considerable amounts of byproducts. In particular, beet leaves represent about 50% of the whole plant’s weight and are usually discarded by the producer or the consumer. This practice reduces significantly the efficiency of the production process and
Nutter, Julia +3 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source