Results 11 to 20 of about 1,179,365 (340)
Current and future alternative therapies for beta-thalassemia major
Biomedical Journal, 2016 Beta-thalassemia is a group of frequent genetic disorders resulting in the synthesis of little or no β-globin chains. Novel approaches are being developed to correct the resulting α/β-globin chain imbalance, in an effort to move beyond the palliative ...
Edouard de Dreuzy +3 more
doaj +3 more sources
Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
Cardiology Research and Practice, 2009 Ivabradine, an If inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction.
Michael Liang +2 more
doaj +3 more sources
Sox9 regulates alternative splicing and pancreatic beta cell function [PDF]
Nature CommunicationsDespite significant research, mechanisms underlying the failure of islet beta cells that result in type 2 diabetes (T2D) are still under investigation.
Sapna Puri +8 more
doaj +4 more sources
betAS: intuitive analysis and visualization of differential alternative splicing using beta distributions [PDF]
RNA, 2022 ABSTRACTNext generation RNA sequencing allows alternative splicing (AS) quantification with unprecedented resolution, with the relative inclusion of an alternative sequence in transcripts being commonly quantified by the proportion of reads supporting it as percent spliced-in (PSI).
Mariana Ascensão-Ferreira +3 more
openalex +3 more sources
An Alternative Approach to Alternative Beta [PDF]
SSRN Electronic Journal, 2007 Hedge fund replication based on factor models is encountering growing interest. In this paper, we investigate the implications of substituting standard rolling windows regressions, which appear ad-hoc, with more effcient methodologies like the Kalman flter.
Teiletche, Jérôme, Roncalli, Thierry
openaire +1 more source
Frontal Beta Transcranial Alternating Current Stimulation Improves Reversal Learning [PDF]
Cerebral Cortex, 2020 Abstract Electroencephalogram (EEG) studies suggest an association between beta (13–30 Hz) power and reversal learning performance. In search for direct evidence concerning the involvement of beta oscillations in reversal learning, transcranial alternating current stimulation (tACS) was applied in a double-blind, sham-controlled and ...
Wischnewski, Miles +3 more
openaire +3 more sources
Tracking Problems, Hedge Fund Replication and Alternative Beta [PDF]
SSRN Electronic Journal, 2009 As hedge fund replication based on factor models has encountered growing interest among professionals and academics, and despite the launch of numerous products (indexes and mutual funds) in the past year, it faced many critics. In this paper, we consider three of the main critiques, namely the lack of reactivity of hedge fund replication and its ...
Roncalli, Thierry, Weisang, Guillaume
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Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?
Cells, 2021 Diabetes mellitus is a pandemic metabolic disorder that results from either the autoimmune destruction or the dysfunction of insulin-producing pancreatic beta cells.
Stephanie Bourgeois +7 more
doaj +1 more source
An Alternative Approach to Computing \(\beta(2k+1)\)
, 2023 This paper presents a new approach to evaluating the special values of the Dirichlet beta function, $\beta(2k+1)$, where $k$ is any nonnegative integer. Our approach relies on some properties of the Euler numbers and polynomials, and uses basic calculus and telescoping series.
Tanabe, Naomi, Wattanawanichkul, Nawapan
openaire +3 more sources
International Journal of Cardiology: Heart & Vasculature, 2020 Beta blockers are a recommended therapy in patients with heart failure with reduced ejection fraction(HFrEF). Beta blockers markedly and unequivocally reduce mortality in patients with heart failure with reduced ejection fraction. However, the beneficial
Xizhen Xu, Dao Wen Wang
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