Results 211 to 220 of about 1,179,365 (340)

Germline and somatic mutations in histologically atypical congenital hyperinsulinism. [PDF]

Front Endocrinol (Lausanne)
Larsen AR, Globa E, Andersen DC, Limbert C, Mattsson ÅL, Nielsen AL, Mortensen MB, Hejbøl EK, Brusgaard K, Detlefsen S, Christesen HT.   +10 more
europepmc   +1 more source

Nonviral human beta defensin‐3 expression in a bioengineered human skin tissue: A therapeutic alternative for infected wounds

, 2012
Angela Gibson, Christina L. Thomas‐Virnig, John M. Centanni, Sandy J. Schlosser, Colette E. Johnston, Kelly F. Van Winkle, Andrea Szilágyi, Li‐Ke He, Ravi Shankar, B. Lynn Allen‐Hoffmann   +9 more
openalex   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Epigenomic, transcriptomic, and proteomic characterization of breast cancer cell line reference samples. [PDF]

Cell Rep Methods
Nepal C, Chen W, Chen Z, Wrobel JA, Xie L, Liao W, Xiao C, Farmer A, Moos M, Jones W, Chen X, Wang C.   +11 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Derivation of a synthetic beta using the Monte Carlo method as an alternative to the comparable company approach for determining the cost of capital

Gonzalo Mandagaran Rivas
openalex   +1 more source

In Vitro Comparison of Ceftolozane-Tazobactam to Traditional Beta-Lactams and Ceftolozane-Tazobactam as an Alternative to Combination Antimicrobial Therapy for Pseudomonas aeruginosa [PDF]

, 2017
Kellie J. Goodlet, David P. Nicolau, Michael D. Nailor   +2 more
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Widespread naturally variable human exons aid genetic interpretation. [PDF]

Nat Commun
Jacobs HN, Gorissen BL, Guez J, Kanai M, Gupta K, Finucane HK, Karczewski KJ, Burge CB.   +7 more
europepmc   +1 more source

The Performance of Alternative Methods for Estimating Equity Betas of Jordan Industries

, 2015
Omar Gharaibeh
openalex   +1 more source