Results 91 to 100 of about 8,236,472 (299)

Alternative care sites and resident exposure in pediatric emergency medicine: Who, what, and where. [PDF]

AEM Educ Train, 2023
Miller KA, Cavallaro S, Hirsch A, Hudgins J, Levy J, Li J, Lipton G, Marchese A, Mannix RC, Monuteaux MC, Schutzman S, Miller AF.   +11 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Analysis of main components of Lake Toba’s water quality in different seasons

Advances in Oceanography and Limnology
Lake Toba is one of the largest lakes in North Sumatra Province, Indonesia. Its waters are used for multiple purposes, constituting an important natural and economic resource.
Yuni Puji Hastuti, Kukuh Nirmala, Manuntun Parulian Hutagaol , Dahri Tanjung, Agit Kriswantriyono, Wildan Nurussalam, Yulia Puspadewi Wulandari, Yuli Siti Fatma   +7 more
doaj   +1 more source

New public-centered child protection system in Korea [PDF]

Clinical and Experimental Pediatrics, 2023
We Sun Shim
doaj   +1 more source

Use of complementary and alternative medicine (CAM) in Sweden: a cross-sectional survey

Scandinavian Journal of Primary Health Care
Aims The aim of this study was to describe the prevalence, associations, and reasons for the use of complementary and alternative medicine (CAM) in Sweden, as well as to further explore possible self-perceived outcomes including adverse effects as well ...
Jenny-Ann Brodin Danell, Kathrin Wode, Miek Jong, Agnete Egilsdatter Kristoffersen, Esther van der Werf, Johanna Hök Nordberg   +5 more
doaj   +1 more source

Childhood Experiences of Alternative Care and Callousness/Unemotionality: A Conceptual Model, Scoping Review, and Research Agenda. [PDF]

Clin Child Fam Psychol Rev, 2023
Pasalich DS, Aquilina B, Hassall A, Goulter N, Xyrakis N, Khoo A.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

ALTERNATIVE CARE IN SOUTH AFRICA

, 2018
Currently, South Africa has an estimated 5,2 million abandoned children in need of care. Facing the highest rate of deaths worldwide from HIV/AIDS, and as a developing country, many children are left in need of care.
Glynis van der Walt, null Glynis van der Walt   +1 more
core   +1 more source

Exploring Alternative Care Platforms for Symptomatic People in the Fight against the Ebola Virus Disease Outbreak. [PDF]

J Immunol Sci, 2023
Onyeneho NG, Aronu NI, Igwe I, Okeibunor J, Diarra T, Diallo AB, Hamadou B, Rodrigue B, Djingarey MH, Yoti Z, N'da Dick M, Yao K, Fall IS, Gueye AS.   +13 more
europepmc   +1 more source