Results 101 to 110 of about 8,236,472 (299)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Apprenticeships and T-levels: an alternative pathway into health care
This article explores Northamptonshire Healthcare Foundation Trust’s (NHFT’s) innovative approach to addressing workforce challenges in the healthcare sector through apprenticeships and T-levels.
Gammon, Lisa
core
, 2011 This bachelor thesis deals with an alternative family care. The main goal is to provide a comprehensive overview of alternative family care, specifically of foster care, to the applicant for custody of the child in alternative family care.
Bruštíková, Martina
core +1 more source
Factors and optimizations of healthcare workers' perception in alternative care facilities. [PDF]
Front Public Health, 2022 Wang H, Luo P, Wu Y, Zeng X.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Youth Who Have Lived in Alternative Care in Nigeria, Zambia, and Zimbabwe: Mental Health and Violence Outcomes in Nationally Representative Data. [PDF]
JAACAP Open, 2023 Neville SE, Okunoren O, Crea TM.
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Safety of an Alternative Care Protocol for EMS Non-Transport in the COVID-19 Pandemic. [PDF]
Prehosp Emerg Care, 2023 Glober N +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Beyond conventional care: exploring complementary and alternative medicine for autoimmune disorders
This literature review provides a comprehensive overview of the use of complementary and alternative modalities for the treatment of autoimmune diseases, which pose a significant challenge in contemporary healthcare, often requiring long-term management ...
Jamal Serhal +5 more
core +1 more source