Results 101 to 110 of about 584,170 (301)

ECOLOGICAL AND ECONOMIC CONFLICTS: AGRICULTURAL USE OR CULTIVATION BIOMASS SECOND GENERATION

Вісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2014
To negotiate the consequences of agricultural modernization as an example of nature Polissya areas in Ukraine. Studies addressing the conceptual foundations of ecological and economic conflict over agricultural use or cultivation of second generation ...
T. Trohlyuk
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Kansas agriculture in 2050: a pathway for climate-resilient crop production

Frontiers in Sustainable Food Systems
IntroductionAdvances in farming technologies and practices have helped farmers to increase crop yields, but continued production increases – while needed to feed a growing global population – are being hindered by climate change and other environmental ...
Kelly M. Suttles, Brian V. Smoliak, Aditya P. Ranade, Samuel F. Potter, Marika Jaeger, Eileen L. McLellan   +5 more
doaj   +1 more source

Procedimientos para Cosechar Lúpulos en Producción a Pequeña Escala

EDIS, 2022
Este artículo explica los procedimientos de cosecha de lúpulo para la producción a pequeña escala (generalmente hasta 5 acres). Este artículo es parte de una serie que examina los desafíos y las oportunidades para la producción de lúpulo en Florida con ...
Shinsuke Agehara, Chistopher DelCastillo, Mariel Gallardo, Weining Wang, Jack Rechcigl, Mariel Gallardo   +5 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

National Agricultural, Research, Extension, Education and Economics Advisory Board Southern Regional Listening Session - Small and Family Farms: Challenges and Needs Alcorn State University, Alcorn, Mississippi [PDF]

The Agricultural and Food Policy Center’s (AFPC) primary purpose is to analyze the economic and financial impacts of alternative government policies on U.S. farming and ranching operations.
Knutson, Ronald D., Richardson, James W., Smith, Edward G.   +2 more
core   +1 more source

Cómo Determinar el Tiempo Óptimo para Cosechar Lúpulos

EDIS, 2022
Este artículo explica cómo determinar el momento óptimo para cosechar el lúpulo. Es parte de una serie que examina los desafíos y las oportunidades de la producción de lúpulo en Florida con base en la investigación del UF/IFAS Gulf Coast Research and ...
Shinsuke Agehara, Mariel Gallardo, Chistopher Del Castillo, Weining Wang, Jack Rechcigl   +4 more
doaj  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Modelling the Impact of 2003 CAP Reform on Crop Production: The case of Durum Wheat in Italy [PDF]

This paper aims to summarize some of the major results emerging from simulating the impact of the CAP reform (the so-called Fischler Reform or Luxembourg Agreement, LA) within the AG-MEMOD model of the agri-food sector in Italy.
Esposti, Roberto, Lobianco, Antonello
core   +1 more source