Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Beyond mitochondria: Alternative energy-producing pathways from all strata of life. [PDF]
Auger C +3 more
europepmc +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Pilot Protection Based on Amplitude Comparison for Renewable Power Teed Lines
Ke Jia +6 more
doaj +1 more source
Modern Hybrid Rye, as an Alternative Energy Source for Broiler Chickens, Improves the Absorption Surface of the Small Intestine Depending on the Intestinal Part and Xylanase Supplementation. [PDF]
Donaldson J +11 more
europepmc +1 more source
Diesel Buses, Oil Prices and Premature Deaths from Particulate Matter: Understanding the Connections, Exploring Solutions [PDF]
In 2000 the Environmental and Energy Study Institute hosted a briefing to discuss the complex issues surrounding diesel buses and alternative-fuel buses.
Randi Blank
core
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Growing and controlling the c‐axis orientation of the aluminium nitride (AlN) thin film on unheated Si (111) substrates using reactive magnetron sputtering are challenging.
Sandeep Sanjeeva +3 more
doaj +1 more source
Evaluation of waste plastic and waste cooking oil as a potential alternative fuel in diesel engine
The generation of plastic waste and waste cooking oil is a serious environmental concern because of worldwide waste disposal issues. At the same time, increasing demand and contemporary geopolitics make fossil fuels a significant worldwide problem.
Amit Kumar +2 more
doaj +1 more source

