Results 31 to 40 of about 924,385 (309)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

2D Ultrasonic Antenna System for Imaging in Liquid Sodium

open access: yesSensors, 2019
Ultrasonic techniques are developed at CEA (French Alternative Energies and Nuclear Energy Commission) for in-service inspection of sodium-cooled reactors (SFRs).
Léonard Le Jeune   +4 more
doaj   +1 more source

Alternative Fuel News, Vol. 2, No. 5 [PDF]

open access: yes, 1999
In this issue of the Alternative Fuel News, the authors remember what happened just 25 years ago (the energy crisis of 1973) and reiterate that foreign oil dependence is still a national issue.
National Renewable Energy Laboratory (U.S.)
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Thermal performance of heat and water recovery systems: Role of condensing heat exchanger material

open access: yesCleaner Engineering and Technology, 2020
A significant amount of sensible and latent heat can be recovered at low temperatures from the flue gas of process heating equipment. However, the condensation of acids and water vapor makes the flue gas a highly-corrosive environment, which is a ...
Negar Mohammadaliha   +2 more
doaj   +1 more source

Development of heat transfer performance in tubular heat exchanger with improved NACA0024 vortex generator

open access: yesCase Studies in Thermal Engineering, 2021
The aim of the experiment was to explore the thermal and fluid flow characteristics inside the tube heat exchanger. To produce and enhance the flow circulations and longitudinal vortex within the tube, an improved NACA0024 vortex generator (VG) was ...
Suabsakul Gururatana   +3 more
doaj   +1 more source

A Review of ESMAP Energy Efficiency Portfolio

open access: yes, 2003
The summary reviews the Energy Sector Management Assistance Programme (ESMAP) activities in energy efficiency (EE), from 1997 to 2002, and evaluates thematic impacts, and lessons of the ESMAP Energy Efficiency
World Bank
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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