Results 151 to 160 of about 376,317 (354)

Facing alternative futures: prospects for and paths to food security in Africa [PDF]

open access: yes
"Food security in Africa has substantially worsened since 1970. Although the proportion of malnourished individuals in Sub-Saharan Africa has remained in the range of 33–35 percent since around 1970, the absolute number of malnourished people in Africa ...
Cline, Sarah A.   +4 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Corrigendum: Alternative futures for Borneo show the value of integrating economic and conservation targets across borders. [PDF]

open access: yesNat Commun, 2016
Runting RK   +11 more
europepmc   +1 more source

Cash Settlement of Lean Hog Futures Contracts Reexamined [PDF]

open access: yes
In 1997 the Chicago Mercantile Exchange replaced its live hog futures contract with a cash settlement mechanism based on a Lean Hog Index. Although cash settlement was expected to increase the use of the contract as a hedging tool, producers and packers ...
Frank, Julieta   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Pedagogies for critical agency: Portals to alternative futures

open access: gold, 2021
Rieta Ganas   +3 more
openalex   +2 more sources

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