Results 131 to 140 of about 3,485,009 (299)

Spectrum of AI futures imaginaries by AI practitioners in Finland and Singapore: The unimagined speed of AI progress [PDF]

open access: yes
AI teases our imagination: People have created various dystopian and utopian imaginaries of the era of AI. Although the key group creating and realizing AI-related futures imaginaries are the technology practitioners who research, develop, and apply AI ...
Hautala Johanna, Heino Hanna
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

How are planetary boundaries operationalised in strategic foresight and futures studies addressing climate change? A scoping review

open access: yesJournal of Innovation and Entrepreneurship
This scoping review examines how the planetary boundaries framework (PB) is operationalised in strategic foresight and futures studies focusing on the global challenge of climate change, and how far these studies engage with alternative economic models ...
Bozica Tzatzanis-Stepanovic
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Alternative Futures of Occupational Therapy and Therapists [PDF]

open access: yes, 2007
Alternatives Futures of Occupational Therapy are explored. These scenarios include: (1) business as usual where the future is known – traditional bureaucracies and traditional caseloads; (2) social justice based focused on rights; (3) transformative ...
Inayatullah, S
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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