Results 111 to 120 of about 3,038,107 (299)
Alternative Futures for the Lao Uplands [PDF]
The multifunctional landscapes of the Lao uplands are characterized both by their diversity of species, land uses and livelihood strategies and, increasingly, the rapid expansion of cash cropping, large-scale land investments and infrastructural ...
Bartlett, Andrew +11 more
core +1 more source
Spectrum of AI futures imaginaries by AI practitioners in Finland and Singapore: The unimagined speed of AI progress [PDF]
AI teases our imagination: People have created various dystopian and utopian imaginaries of the era of AI. Although the key group creating and realizing AI-related futures imaginaries are the technology practitioners who research, develop, and apply AI ...
Hautala Johanna, Heino Hanna
core +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Three electricity futures: Monitoring the emergence of alternative system architectures
The electricity system is in transition, but whereto? To large-scale global or regional grids or to self-sufficient disconnected prosumers? Although numerous studies have previously dealt with the future of the electricity system, there is a lack of ...
Ahlborg, Helene +8 more
core +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
"Volatility Models of Currency Futures in Developed and Emerging Markets" [PDF]
This paper examines volatility models of currency futures contracts for three developed markets and two emerging markets. For each contract, standard models of the Unbiased Expectations Hypothesis (UEH) and Cost-of-Carry hypothesis (COC) are extended to ...
Michael McAleer +2 more
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
No alternatives? Animal experimentation and the future of research
published
openaire +4 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

