Results 61 to 70 of about 3,038,107 (299)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Alternative futures of China: A macrohistorical approach

open access: yes, 2016
This paper is an heuristic application in understanding China's alternative futures by looking at the deeper patterns of history and social change developed by four macrohistorians: Sima Qian, Prabhat Ranjan Sarkar, Pitirim Sorokin and Oswald Spengler ...
Jeanne Hoffman
core   +1 more source

Anticipating Alternative Futures for the Platform Economy

open access: yesTechnology Innovation Management Review, 2017
Despite the considerable hype around platforms, our understanding of what the platform economy means and what drivers will define future development trajectories is limited.
Mikko Dufva   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Willamette Valley Summary Report

open access: yes, 2000
The Willamette Valley Alternative Futures project attempts to describe future development patterns in the Willamette Valley, and their impacts on farm and forest production, and on the costs of public ...
ECONorthwest
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Alternative futures of rural areas in the EU [PDF]

open access: yes, 2009
In this study alternative futures of rural areas in the EU are explored. For this purpose, a comparative analysis of seven scenario studies of rural areas in the EU was conducted.
Jansson, K.M., Terluin, I.J.
core  

Defining ‘Future Generations’: Epistemic Considerations on Conceptualizing a Future-Oriented Domain in Policy And Law-Making [PDF]

open access: yes
The rights of future generations generates increasing interest among both academics and policymakers. This article identifies two key gaps in the emerging literature.
Ahlqvist Toni   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy