Results 81 to 90 of about 376,317 (354)

Unlocking futures literacy: essential skills for students for an evolving world

open access: yesCogent Education
In an era of global uncertainty, educational systems worldwide face challenges in preparing learners for unknown futures. While futures literacy—the capacity to anticipate, critique, and co-create alternative futures—is gaining recognition, a gap remains
Yu Wang, Yue Zhu
doaj   +1 more source

Implications of Crop Yield and Revenue Insurance for Producer Hedging

open access: yesJournal of Agricultural and Resource Economics, 2000
New types of crop insurance have expanded the tools from which crop producers may choose to manage risk. Little is known regarding how these products interact with futures and options. This analysis examines optimal futures and put ratios in the presence
Keith H. Coble   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Comparing Hedging Effectiveness: An Application of the Encompassing Principle

open access: yesJournal of Agricultural and Resource Economics, 2004
An empirical methodology is developed for statistically testing the hedging effectiveness among competing futures contracts. The presented methodology is based on the encompassing principle, widely used in the forecasting literature, and applied here to ...
Dwight R. Sanders, Mark R. Manfredo
doaj   +1 more source

ALTERNATIVE FUTURES OF RURAL AREAS IN THE EU: A COMPARATIVE ANALYSIS OF SCENARIO STUDIES [PDF]

open access: yes
What does rural Europe look like in 2030? Is agriculture still the main land user? In recent years, studies such as ESPON, Eururalis, SCENAR2020, SENSOR, SEAMLESS and PRELUDE have tried to address these questions.
Jansson, Kristina M., Terluin, Ida J.
core   +1 more source

Methodology for the comparative assessment of the Satellite Power System (SPS) and alternative technologies [PDF]

open access: yes, 1980
The energy systems concerned are the satellite power system, several coal technologies, geothermal energy, fission, fusion, terrestrial solar systems, and ocean thermal energy conversion. Guidelines are suggested for the characterization of these systems,
Buehring, W.   +9 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Critical Discourse Analysis of Persuasive Appeals and Ideological Frameworks in Harris and Biden’s 2024 Campaign Rhetoric

open access: yesResearch in English Language Pedagogy
Political campaign rhetoric is a crucial tool for shaping public perception, mobilizing support, and influencing electoral outcomes, especially in highly mediated and polarized contexts.
Sabaa Zaid Jawad Witwit   +3 more
doaj  

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