Results 81 to 90 of about 3,589,070 (301)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Do alternative measures of GDP affect its interpretation? [PDF]

open access: yes
Gross domestic product's high correlation with unemployment and inflation makes it a key measure of the U.S. economy. Yet the somewhat arbitrary nature of the GDP construction process complicates interpretation and measurement of the indicator.
Bart Hobijn, Charles Steindel
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Alternative Measures of Homeownership Gaps Across Segregated Neighboorhoods [PDF]

open access: yes
The dramatic rise in the U.S. homeownership rate from 64% in 1996 to almost 70% in 2005 has prompted increased attention to the relation between homeownership and demographic characteristics of households.
Anthony Yezer, Paul Carrillo
core  

Repeat Maltreatment in Alaska: Assessment and Exploration of Alternative Measures [PDF]

open access: yes, 2015
Most deaths and serious injuries among children who are abused or neglected are preceded by multiple reported instances of maltreatment. The Office of Children Services (OCS), Alaska’s child protection agency, is very concerned about repeat ...
Passini, Jessica, Vadapalli, Diwakar
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Alternative Measures in Macedonia

open access: yesAcademic Journal of Interdisciplinary Studies, 2014
Alternative measures represent modern reforms to penal sanctions.With legislative changes of 2004 the Macedonian Penal Code has provided alternative measures as types of criminal sanctions.Based on the practice of other states and their effect in practice, this legislation has seen it appropriate to its provisions to foresee these types of alternative ...
openaire   +2 more sources

ALTERNATIVE MEASURES OF FARM SIZE: TRENDS AND DETERMINANTS [PDF]

open access: yes
Because of policy interest in the size distribution of farms, there is an interest in understanding the causes of changing farm sizes. This paper addresses an overlooked issue in the literature on the determinants of farm size, namely, the empirical ...
Ahearn, Mary Clare, Yee, Jet
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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