Results 151 to 160 of about 7,463,462 (316)
AI-driven Alternative Medicine: A Novel Approach to Drug Discovery and Repurposing [PDF]
arXivAIAltMed is a cutting-edge platform designed for drug discovery and repurposing. It utilizes Tanimoto similarity to identify structurally similar non-medicinal compounds to known medicinal ones. This preprint introduces AIAltMed, discusses the concept of `AI-driven alternative medicine,' evaluates Tanimoto similarity's advantages and limitations, and ...
arxiv
Estimating Individualized Treatment Rules for Ordinal Treatments [PDF]
arXiv, 2017 Precision medicine is an emerging scientific topic for disease treatment and prevention that takes into account individual patient characteristics. It is an important direction for clinical research, and many statistical methods have been recently proposed. One of the primary goals of precision medicine is to obtain an optimal individual treatment rule
arxiv
Journal of Evidence-Based Complementary & Alternative Medicine, 2016 Although modern treatments have achieved much progress in blood sugar control in recent decades, evidences indicate that complementary and alternative treatments are very common in diabetic patients.
Akbar Sheikhrabori +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source
Kava - the unfolding story: Report on a work-in-progress. [PDF]
Journal of Alternative and Complementary Medicine, 8(3), 237 ...
Denham, Alison +2 more
core
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
Random Forests of Interaction Trees for Estimating Individualized Treatment Effects in Randomized Trials [PDF]
Statistics in Medicine, 37(17): 2547-2560, 2018, 2017 Assessing heterogeneous treatment effects has become a growing interest in advancing precision medicine. Individualized treatment effects (ITE) play a critical role in such an endeavor. Concerning experimental data collected from randomized trials, we put forward a method, termed random forests of interaction trees (RFIT), for estimating ITE on the ...
arxiv
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
A Sequential Density-Based Empirical Likelihood Ratio Test for Treatment Effects [PDF]
Statistics in Medicine (2019), 2018 In health-related experiments, treatment effects can be identified using paired data that consist of pre- and post-treatment measurements. In this framework, sequential testing strategies are widely accepted statistical tools in practice. Since performances of parametric sequential testing procedures vitally depend on the validity of the parametric ...
arxiv
Bangladesh Journal of Pharmacology, 2013 In the present study, we evaluated the protective effects of the aqueous-methanolic extract of Suaeda fruticosa (500 mg/kg and 750 mg/kg b.w., p.o) against paracetamol-induced hepatotoxicity in rabbits. Silymarin 100 mg/kg, p.o.
Jalil Ur Rehman +6 more
doaj +1 more source