Results 151 to 160 of about 2,394,698 (264)

Beyond IV push: alternative methods for management of acute pain in SCD. [PDF]

Hematology Am Soc Hematol Educ Program
Azul M, Brandow AM.
europepmc   +1 more source

Alternative methods for skeletal maturity estimation with the EOS scanner-Experience from 934 patients. [PDF]

PLoS One, 2022
Schlégl ÁT, O'Sullivan I, Varga P, Than P, Vermes C.   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Alternative Methods of Fixation for Anterior Tibialis Transfer in Residual Clubfoot Deformity. [PDF]

J Pediatr Soc North Am
Wilson S, Bellaire LL, Noonan KJ.
europepmc   +1 more source

Development of Synthetic Aqueous Oil and Grease Standards for Determination of TOG in Produced Water: Evaluation of Alternative Methods for Application in an Offshore Environment. [PDF]

ACS Omega, 2023
Ferraço Brant V, Carvalho RM, Martins MO, Marques FFC, Fidalgo-Neto AA.   +4 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Pig welfare and ethical considerations during abattoir stunning: CO₂ vs. alternative methods such as argon gas. [PDF]

Front Vet Sci
Mace JL, Knight A.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The Progression-Free-Survival Ratio in Molecularly Aided Tumor Trials: A Critical Examination of Current Practice and Suggestions for Alternative Methods. [PDF]

Biom J
Edelmann D, Terzer T, Horak P, Schlenk R, Benner A.   +4 more
europepmc   +1 more source

Alternative Methods to Current In Vivo Procedures to Address the 3Rs Tenet in Rabies Proficiency Testing. [PDF]

Viruses, 2022
Zorzan M, Gourlaouen M, Leopardi S, De Benedictis P.   +3 more
europepmc   +1 more source