Results 31 to 40 of about 2,394,698 (264)

Establishing a 3D Spheroid Model of Cholinergic Neurons from SH-SY5Y Cells for Neurotoxicity Assessment

Toxins
The nervous system maintains homeostasis and coordinated behavior through complex neuronal and glial cells. Traditional models, such as primary rodent neurons and human-induced pluripotent stem cell (hIPSC)-derived neurons, have advanced our ...
Felipe Franco-Campos, Mónica Fernández-Franzón, Yelko Rodríguez-Carrasco, María-José Ruiz   +3 more
doaj   +1 more source

The Growing Importance of Three-Dimensional Models and Microphysiological Systems in the Assessment of Mycotoxin Toxicity

Toxins, 2023
Current investigations in the field of toxicology mostly rely on 2D cell cultures and animal models. Although well-accepted, the traditional 2D cell-culture approach has evident drawbacks and is distant from the in vivo microenvironment.
Veronica Zingales, Maria Rosaria Esposito, Noemi Torriero, Mercedes Taroncher, Elisa Cimetta, María-José Ruiz   +5 more
doaj   +1 more source

Differential Proliferation Effect of the Newly Synthesized Valine, Tyrosine and Tryptophan–Naphthoquinones in Immortal and Tumorigenic Cervical Cell Lines

Molecules, 2020
We previously showed that microwave assisted synthesis is the best method for the synthesis of naphthoquinone amino acid and chloride-naphthoquinone amino acid derivatives by a complete evaluation of reaction conditions such as stoichiometry, bases, and ...
Sergio Córdova-Rivas, Jorge Gustavo Araujo-Huitrado, Ernesto Rivera-Avalos, Ismailia L. Escalante-García, Sergio M. Durón-Torres, Yamilé López-Hernández, Hiram Hernández-López, Lluvia López, Denisse de Loera, Jesús Adrián López   +9 more
doaj   +1 more source

The action of clove (Syzygium aromaticum ) and thyme ( Thymus vulgaris) essential oils in the control of Acanthhoscelides obtectus (Coleoptera: Chrysomelidae) in laboratory

Anais da Academia Brasileira de Ciências, 2023
The objective of this study was to assess the efficiency of essential oils of cloves (Syzygium aromaticum) and thyme (Thymus vulgaris) on the control of Acanthoscelides obtectus in laboratory conditions.
ADÉLIO Z. MUSSALAMA, CRISTIANO M. TEIXEIRA, ADRISE M. NUNES, CLAUDIO M.P. PEREIRA, FLÁVIO R.M. GARCIA   +4 more
doaj   +1 more source

Antibacterial Activity and Antibiotic Potentiation of Melipona rufiventris Bioproducts Against Multidrug-Resistant Bacteria

Natural Product Communications
Objective Based on this premise, the present study aimed to evaluate the antibacterial activity of ethanolic extracts of wax (EECMr) and fermented pollen (EEPMr), as well as pure honey (HMr) from Melipona rufiventris , against multi-resistant strains of ...
Antonio Henrique Bezerra, Suieny Rodrigues Bezerra, Cristina Rodrigues dos Santos Barbosa, Débora Feitosa Muniz, Débora de Menezes Dantas, Zildene de Sousa Silveira, Nair Silva Macêdo, Thaís Ferreira da Silva, Cícera Datiane de Morais Oliveira-Tintino, Henrique Douglas de Melo Coutinho, José Galberto Martins da Costa, Hélcio Silva dos Santos, Francisco Assis Bezerra da Cunha   +12 more
doaj   +1 more source

Alternate Methods in Reservoir Simulation [PDF]

, 2001
As time progresses, more and more oil fields and reservoirs are reaching maturity; consequently, secondary and tertiary methods of oil recovery have become increasingly important in the petroleum industry. This significance has added to the industry's interest in using simulation as a tool for reservoir evaluation and management to minimize costs and ...
Guadalupe I. Janoski, Andrew H. Sung
openaire   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Cyclopiazonic Acid Induces Mitochondrial Oxidative Stress in SH-SY5Y Cells: Protective Effects of Extra Virgin Olive Oil Phenolics

Toxins
Cyclopiazonic acid (CPA), a neurotoxin produced by Penicillium and Aspergillus genera, induces oxidative stress and neuronal damage, mechanisms implicated in neurodegenerative diseases.
Carmen Martínez-Alonso, Yelko Rodríguez-Carrasco, María-José Ruiz   +2 more
doaj   +1 more source

Methods for Collecting Data Based Upon an Eastern Paradigm of Evaluation

Journal of MultiDisciplinary Evaluation, 2019
Background: This is one in a series of articles in which the authors attempt to relate Eastern philosophy to contemporary program planning and evaluation.
Craig Russon
doaj   +1 more source