Results 81 to 90 of about 786,469 (327)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Metric properties of alternating Oppenheim expansions [PDF]

open access: yesActa Arithmetica, 2003
The series representation \[ x= \frac{1}{d_1}+ \frac{a_1(d_1)} {b_1(d_1)} \frac{1}{d_2}+ \frac{a_1(d_1)\cdots a_n(d_n)} {b_1(d_1)\cdots b_n(d_n)} \frac{1}{d_{n+1}}+\cdots, \] \(a_n(j)\), \(b_n(j)\) \((n\geq 1)\) are positive integer valued functions of the integers \(j\geq 1\), \(d_n\) are positive integers, \(h_n(j)= \frac{a_n(j)} {b_n(j)} j(j-1)\), \(
Galambos, János   +2 more
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Research on alternative measures in the F1000 system with Google Scholar citation index

open access: yesIranian Journal of Information Processing & Management, 2016
The purpose of this study was to assess the relationship between altmetrics measures of F1000 website and citation Indexes of Google scholar. Applied research and survey methods, citation analysis, and webometrics with descriptive analytical approach are
Saeideh Ebrahimy, Fatemeh Setareh
doaj  

Alternative metrics to measure EMS system performance

open access: yesJournal of the Operational Research Society, 2017
In the development of strategy for the response to emergent incidents, emergency medical services (EMS) organizations must properly manage their resources while also adhering to response time mandates established by contractual agreements. Performance of an EMS system is typically measured by focusing on the response time of its first responders ...
Capar, Ibrahim   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Alternative household water affordability metrics using water bill delinquency behavior

open access: yesEnvironmental Research Letters
Rising water prices threaten affordable access to basic water service in the U.S., especially in low-income communities. Faced with unaffordable water bills, households may use less water than is healthy, forgo other essential services, or fall behind on
Jennifer B Skerker   +4 more
doaj   +1 more source

Conductance fluctuations in quasi-two-dimensional systems: a practical view

open access: yes, 2012
The universal conductance fluctuations of quasi-two-dimensional systems are analyzed with experimental considerations in mind. The traditional statistical metrics of these fluctuations (such as variance) are shown to have large statistical errors in such
A. A. Bobkov   +6 more
core   +1 more source

Alternative Metrics to Select Motors for Quasi-Direct Drive Actuators [PDF]

open access: green, 2022
Karthik Urs   +3 more
openalex   +1 more source

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