Results 101 to 110 of about 247,846 (249)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

A comparison of metrics for estimating phylogenetic signal under alternative evolutionary models

open access: yesGenetics and Molecular Biology, 2012
Several metrics have been developed for estimating phylogenetic signal in comparative data. These may be important both in guiding future studies on correlated evolution and for inferring broad-scale evolutionary and ecological processes (e.g ...
José Alexandre F. Diniz-Filho   +3 more
doaj  

Eigenvalue bounds and alternating rank-metric codes

open access: yesJournal of Algebra and Its Applications
In this note, we apply a spectral method to the graph of alternating bilinear forms. In this way, we obtain upper bounds on the size of an alternating rank-metric code for given values of the minimum rank distance. We computationally compare our results with Delsarte’s linear programming bound, observing that they give the same value.
Aida Abiad   +2 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Analysis of classification metric behaviour under class imbalance

open access: yesEgyptian Informatics Journal
Class imbalance is the phenomenon defined as skewed target variable distributions in a dataset. In other words class imbalance occurs when a dataset has an unequal proportion of target variables assigned to the instances in the dataset.
Jean-Pierre van Zyl   +1 more
doaj   +1 more source

An Alternative Variational Principle for Geodesics of a Randers Metric

open access: yesAdvanced Nonlinear Studies, 2009
Abstract We present an alternative variational principle for the geodesics of a Randers metric. We define a functional I on the manifold of H 1,2 curves joining two points on a Randers manifold (M, F) defined by a Riemannian metric g and a differential form ω. The functional
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Metric-Driven Voronoi Diagrams: A Comprehensive Mathematical Framework

open access: yesComputation
Voronoi partitioning is a fundamental geometric concept with applications across computational geometry, robotics, optimization, and resource allocation.
Vishnu G. Nair
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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