Results 111 to 120 of about 8,418,894 (311)

Office of Innovative Partnerships & Alternative Funding as of April 7, 2011 [PDF]

open access: yes, 2011
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 1, 2014)Mode of ...

core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Texture-based Visualization of Metrics on Software Architectures [PDF]

open access: yes, 2008
We present a method that combines textures, blending, and scattered-data interpolation to visualize several metrics defined on overlapping areas-of-interest on UML class diagrams.
Telea, Alexandru   +5 more
core   +1 more source

Experience with an easily computed metric for ranking alternative parsess [PDF]

open access: yesProceedings of the 20th annual meeting on Association for Computational Linguistics -, 1982
This brief paper, which is itself an extended abstract for a forthcoming paper, describes a metric that can be easily computed during either bottom-up or top-down construction of a parse tree for ranking the desirability of alternative parses. In its simplest form, the metric tends to prefer trees in which constituents are pushed as far down as ...
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Mapping the Generations of Research Impact Science: A Scoping Review of Metrics, Frameworks, and Predictive Approaches [PDF]

open access: yesJournal of Library and Information Studies
This scoping review systematically examines the evolution of research impact assessment frameworks, categorising their development into 4 generations.
Mudassar Arsalan   +2 more
doaj   +1 more source

Alternative Metrics as a New Perspective for Measuring Scientific Activity in Light of Technological Changes

open access: yesمجلة الآداب و العلوم الإجتماعية
Scientific research has moved from the narrow and closed circle of official scientific publishing channels to an open and free environment enabled by Web 2.0 technologies.
هجيرة بن بوزيد   +1 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Feedback-Based Gameplay Metrics and Gameplay Performance Segmentation: An audio-visual approach for assessing player experience. [PDF]

open access: yes, 2014
Gameplay metrics is a method and approach that is growing in popularity amongst the game studies research community for its capacity to assess players’ engagement with game systems.
Marczak, Raphaël
core  

Decoding a Class of Alternant Codes for the Lee Metric

open access: yesElectronic Notes in Discrete Mathematics, 2001
Abstract We investigate a class of Lee-metric alternant codes with symbols in Z p n , establishing a lower bound on the minimum Lee distance where certain restrictions are placed on the code parameters. Corresponding to this bound we have devised two decoding algorithms.
openaire   +1 more source

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