Results 51 to 60 of about 223,616 (286)

The mediating effect of self-esteem, depression and anxiety between satisfaction with body appearance and problematic Internet use [PDF]

, 2013
Background and objectives: Given that dissatisfaction with bodily appearance can sometimes lead to the avoidance of personal contacts and the increase of internet use, this study examines this relationship.
Demetrovics, Z, Griffiths, MD, Koronczai, B, Kun, B, Kökönyei, G, Nagygyörgy, K, Pápay, O, Urbán, R   +7 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Predicting personality disorders based on Zuckerman's alternative five-factor model and ego strength [PDF]

, 2017
Background and aims: Personality disorders have a wide range and have pervasive effects on the individual life and interpersonal relationships. Understanding the underlying factors of personality disorders causes more accurate understanding and ...
Basharpoor, S., Einy, S.
core  

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

A closer look at the Test of Personal Intelligence (TOPI) [PDF]

, 2017
Personal intelligence involves the capacity to reason about personality and personality-related information. Studying ability-based measures of personal intelligence creates a virtuous cycle of better measurement and better theoretical understanding.
Caruso, David R., Mayer, John D., Panter, A. T.   +2 more
core   +2 more sources

Response perseveration and the triarchic model of psychopathy in an undergraduate sample. [PDF]

, 2020
This study aimed to extend previously reported links between distinctive configurations of traits in the psychopathic personality and maladaptive response perseveration, by examining performance in the Card Perseveration Task (CPT) within the ...
Branchadell, Victoria, Molto, Javier, Poy, Rosario, Ribes Guardiola, Pablo, Segarra, Pilar   +4 more
core   +1 more source

Comparing the clinical utility of the alternative model for personality disorders to the Section II personality disorder model: A randomized controlled trial.

Personality Disorders: Theory, Research, and Treatment
The alternative model for personality disorders (AMPD) has been extensively studied over the past decade, but to date there is no direct comparison of the clinical utility of the AMPD model relative to the Section II personality disorder (PD) model in an ecologically valid design.
Laura C. Weekers, Joost Hutsebaut, Hilde De Saeger, Jan H. Kamphuis   +3 more
openaire   +3 more sources

Changes in the classification of personality disorders: Comparing the DSM–5 Section II personality disorder model to the alternative model for personality disorders using structured clinical interviews.

Personality Disorders: Theory, Research, and Treatment, 2022
The current study examined the continuity of personality disorder (PD) diagnoses from Section II to Section III (alternative model for personality disorders [AMPD]) when using structured interviews. We investigated the continuity both in terms of stability of prevalence rates and in terms of convergent validity.
Laura C. Weekers, Joost Hutsebaut, Johannes Zimmermann, Jan H. Kamphuis   +3 more
openaire   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source