Results 141 to 150 of about 94,660 (301)
A number of papers have appeared with the purpose of generalizing Albert’s long-standing result [l, 21 that a simple right alternative algebra of finite dimension over a field of characteristic f2 that has a unit element e and an idempotent c # e is necessarily alternative.
openaire +2 more sources
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
The world is changing: ethics and genre development in three twentieth-century high fantasies. [PDF]
This thesis examines three genre high fantasy texts published between 1954 and 2001: J. R. R. Tolkien’s 'The Lord of the Rings', Ursula K. Le Guin’s 'Earthsea' cycle and Patricia A. McKillip’s 'The Riddle-Master’s Game'.
Le Lievre, Kerrie Anne
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
“Polymerization” of Bimerons in Quasi-Two-Dimensional Chiral Magnets with Easy-Plane Anisotropy
We re-examine the internal structure of bimerons, which are stabilized in easy-plane chiral magnets and represent coupled states of two merons with the same topological charge |1/2| but with opposite vorticity and the polarity.
Natsuki Mukai, Andrey O. Leonov
doaj +1 more source
An Alternate Ring-Ring Design for eRHIC
I present here a new ring-ring design of eRHIC, a polarized electron-ion collider based on RHIC at BNL. This alternate eRHIC design utilizes high repetition rate colliding beams and is likely able to deliver the performance to meet the requirements of the science program with low technical risk and modest accelerator R&D.
openaire +2 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

