Results 121 to 130 of about 94,858 (343)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Additivity of elementary maps on alternative rings

open access: yes, 2019
Let ℜ and ℜ′ be alternative rings. In this article we investigate the additivity of surjective elementary maps of ℜ × ℜ′.
Ferreira, B.L.M.
core   +1 more source

The ALMA survey to Resolve exoKuiper belt Substructures (ARKS)

open access: yesAstronomy & Astrophysics
Context. Dusty discs detected around main-sequence stars are thought to be signs of planetesimal belts in which the dust distribution is shaped by collisional and dynamical processes, including interactions with gas if present. The debris disc around the
Jankovic M. R.   +29 more
doaj   +1 more source

Production, detection, storage and release of spin currents

open access: yesBeilstein Journal of Nanotechnology, 2015
Background: Quantum rings connected to ballistic circuits couple strongly to external magnetic fields if the connection is not symmetric. Moreover, properly connected rings can be used to pump currents in the wires giving raise to a number of interesting
Michele Cini
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation of Cannulated Compression Headless Screw (CCHS) as an alternative implant in comparison to standard S1-S2 screw fixation of the posterior pelvis ring: a biomechanical study [PDF]

open access: gold, 2023
Till Berk   +8 more
openalex   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Assessment of restrained shrinkage cracking of concrete through elliptical rings [PDF]

open access: yes, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An elliptical ring test method is presented to replace the circular ring test method for assessing cracking potential of concrete and other cement-based ...
Oladiran, Olayinka Gbolahan
core  

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