Results 101 to 110 of about 94,660 (301)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of Chemistry, 2017 The process of N-alkylation of several pyrroles, indoles, and derivative heterocycles is herein described, using quaternary ammonium salts as the source of an alkylating agent.
Carlos A. González-González +7 more
doaj +1 more source
Journal of Combinatorial Theory, 1967 AbstractAn example is presented that ansevers in the negative the question of whether the square of every commutator need always lie in the nucleus. Also, we show the existence of specific nilpotent elements in the free alternative ring on four or more generators, and prove abstractly the existence of an ideal I≠0, and I2=0.
Humm, Margaret M., Kleinfeld, Erwin
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mentha longifolia lowers blood pressure in anesthetized rats through multiple pathways
Bangladesh Journal of Pharmacology, 2016 This study was aimed to investigate the effect of the extract of Mentha longifolia on blood pressure and the possible mechanisms. In anesthetized rats, the crude extract of M.
Abdul Jabbar Shah +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Parastrophic invariance of Smarandache quasigroups [PDF]
, 2006 The study of the Smarandache concept in groupoids was initiated by W.B. Vasantha Kandasamy in [18]. In her book and first paper on Smarandache concept in loops, she defined a Smarandache loop as a loop with at least a subloop which forms a subgroup ...
Gbolahan, Temitope
core +1 more source
You-qi chuyunObjective Seal rings and gaskets are deemed indispensable sealing components for the safe operation of pure hydrogen/ hydrogen-enriched compressed natural gas pipelines.
Jianlu ZHU +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On generalizing alternative rings [PDF]
Proceedings of the American Mathematical Society, 1974 Consider a ring R R that satisfies the identity
openaire +1 more source