Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
BDC-YOLO: A Novel Architecture Coupling Dynamic Serpentine Convolutions with Bi-Level Routing Attention for Road Defect Detection. [PDF]
Yang B, Sheng H, Geng C, Chen C, Lian H.
europepmc +1 more source
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
MoR-Swin: Efficient Vision Transformer Using Mixture of Recursions. [PDF]
Ai Y, Gao T, Lin Z, Yang L, Chang Q.
europepmc +1 more source
Cosine Similarity Distillation Vision Mixture-of-Experts for Intelligent Housing-Dimensional Urban Physical Examinations. [PDF]
Zhao K +7 more
europepmc +1 more source
Single-stage multidisciplinary management of contiguous infection involving infected abdominal aortic aneurysm and lumbar spondylodiscitis following infective endocarditis. [PDF]
Iida J +6 more
europepmc +1 more source
FMDNet: Spatial-frequency feature routing for low-dose CT denoising. [PDF]
Yao Y +6 more
europepmc +1 more source
Intelligent power underwater wireless sensor networks for marine environmental monitoring using a hybrid marine predator-Henry gas solubility optimization approach. [PDF]
Yanhao W +5 more
europepmc +1 more source
Modeling IN out-of-hospital emergency medical services-a scoping review of approaches and applications. [PDF]
Zahorka F +4 more
europepmc +1 more source
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