Results 151 to 160 of about 2,948,586 (288)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

The policy construction of illegal markets: Exploring variation, success, failure, and unintended consequences. [PDF]

Proc Natl Acad Sci U S A
Paoli L, Reuter P.
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Evaluating AI-assisted customer verification for synthetic nucleic acid screening. [PDF]

Front Bioeng Biotechnol
Acelas A, Palya H, Flyangolts K, Fady PE, Nelson C.   +4 more
europepmc   +1 more source

Alternative sanctions in the juvenile prison population

, 2014
Todo tema que sea abordado desde el análisis de las políticas públicas es interesante porque permite descubrir, desde una óptica que pretende ser objetiva, si las decisiones o la gestión estatal van por el camino adecuado y el estudio de las sanciones penales juveniles es uno de esos temas.
openaire   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Alternative Sanctions in Czech Criminal Law

, 2013
This thesis deals with the theme of alternative forms in Czech criminal law, especially with the matters of alternative sanctions. It is divided into sixteen chapters and begins by the explanation of the term and purpose of punishment (Chapter Two). Then
Huláková, Markéta
core  

Alternative criminal sanctions for international crimes in transitional contexts

This dissertation assessed from a legal-doctrinal, theoretical, and empirical perspective whether ‘alternative criminal sanctions’ may be ‘adequate’ for international crimes being punished in transitional contexts, according to international (criminal) law and transitional justice theory.
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Alternative sanctions to imprisonment

, 2012
Bu tez, üç bölümden müteşekkildir. Birinci bölümde, onarıcı adalet yap-tırımı ve toplum içerisinde infaz edilen ceza hukuku yaptırımları, cezalandır-maktaki amaçlar bakımından incelenmiştir.
Maden, Mehmet
core