Results 171 to 180 of about 312,791 (347)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Banning loot boxes for minors: A public health framework and the case of Brazil. [PDF]

J Behav Addict
Spritzer DT, Fortim I, Roza TH, Kessler FHP, Kim HS.   +4 more
europepmc   +1 more source

Alternative Investigation and Sanctioning Systems for Corporate and Corporate-Related Crime in Finland

, 2019
Raimo Lahti, Miikka K Rainiala
openalex   +1 more source

AN OVERVIEW OF THE INTERNATIONAL SCIENTIFIC-PROFESSIONAL MEETING AT THE APPELLATE COURT IN NIŠ WITHIN THE PROJECT "STRENGTHENING THE PROBATION AND THE SYSTEM OF ALTERNATIVE SANCTIONS IN MONTENEGRO AND SERBIA" NIŠ, 4TH DECEMBER 2018

, 2019
Dijana Janković
openalex   +2 more sources

Guilds, Efficiency, and Social Capital: Evidence from German Proto-Industry [PDF]

This paper analyzes an early modern German economy to test alternative theories about guilds. It finds little evidence to support recent hypotheses arguing that guilds corrected market failures relating to product quality, training, and innovation.
Sheilagh Ogilvie
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Dark side of the principles of non-discrimination and proportionality: the case of mandatory vaccination. [PDF]

J Med Ethics
Horák F, Dienstbier J.
europepmc   +1 more source

Alternative Sanctions and the Federal Tax Law: Symbols, Shaming, and Social Norm Management as a Substitute for Effective Tax Policy

, 2004
Michael S. Kirsch
openalex   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

How peer mechanism impacts loan repayment in a Self-help group?: An empirical study in India. [PDF]

PLoS One
Malhotra N.
europepmc   +1 more source