Results 181 to 190 of about 312,791 (347)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The effectiveness of interventions in reducing economic inactivity for people with long term health conditions and disabilities in the United Kingdom: a systematic review. [PDF]

BMC Public Health
Haighton C, Wales J, Wilkie R, Gray J, Crawshaw P.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Artificial intelligence in oncology publishing: a systematic review and policy analysis of high-impact journals. [PDF]

Front Oncol
Giusti R, Filetti M, Lombardi P, Lo Bianco F, Sganga S, Giovagnoli T, Iannantuono GM, Spinazzola A, Santini D, Mariniello M, Porzio G, Ibrahim M, Daniele G.   +12 more
europepmc   +1 more source

Transformation of cross-border financial transactions under sanctions pressure: analysis of alternative payment mechanisms and strategies for ensuring Russia's economic stability

Oksana Vladimirovna Madatova
openalex   +1 more source

Trade Sanctions and Child Labour: Quest for an Alternative Policy

, 2003
Sarbajit Chaudhuri
openalex   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The Impact of Economic Sanctions on Health and Strategies for Mitigation: A Glance at the Case of Iran. [PDF]

Int J Prev Med
Mohammadshahi M, Rakhshan ST, Nateghinia S, Damiri S, Sakha MA, Mostafavi H, Nasiri T, Ghorbani M, Shams L, Jahanmehr N.   +9 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Mapping the regulatory landscape for environmental sustainability of medical device practices within the European Union. [PDF]

Eur J Public Health
Zarro M, Ferranti A, Garagozzo G, Fico G, Pecchia L.   +4 more
europepmc   +1 more source