Results 131 to 140 of about 344,150 (327)

Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda, Hyo‐Min Kim, Nicole Battaglia, Joshua Rong, Amy Tam, Enrique Gonzalez Saez‐Diez, Cornelius F. Boerkoel, Afshin Saffari, Vicente Quiroz, Luca Schierbaum, Zainab Zaman, Katerina Bernardi, Darius Ebrahimi‐Fakhari   +12 more
wiley   +1 more source

Alternative splicing in stem cells and development: research progress and emerging technologies

Cell Regeneration
Alternative splicing is a key regulatory mechanism that generates transcriptomic diversity by selectively splicing pre-RNA molecules in different ways, leading to the production of multiple RNA isoforms from a single gene. This process is crucial for the
Yan Jin, XiaoLin Liang, Xiangting Wang
doaj   +1 more source

A Ralstonia solanacearum Effector Targets Splicing Factor SR34a to Reprogram Alternative Splicing and Regulate Plant Immunity

Plants
Alternative splicing is a critical post-transcriptional regulatory mechanism in eukaryotes. While infection with Ralstonia solanacearum GMI1000 significantly alters plant alternative splicing patterns, the underlying molecular mechanisms remain unclear ...
Yunyun Li, Song Kou
doaj   +1 more source

Splicing and alternative splicing in rice and humans [PDF]

BMB Reports, 2013
Rice is a monocot gramineous crop, and one of the mostimportant staple foods. Rice is considered a model species formost gramineous crops. Extensive research on rice hasprovided critical guidance for other crops, such as maize andwheat.
Zhiguo E, Lei Wang, Jianhua Zhou
doaj  

A novel form of human neuropsin, a brain‐related serine protease, is generated by alternative splicing and is expressed preferentially in human adult brain [PDF]

, 1999
Shinichi Mitsui, Nobuo Tsuruoka, Kyoko Yamashiro, Hiroshi Nakazato, Nozomi Yamaguchi   +4 more
openalex   +1 more source

Fiber Bragg Gratings with Micro‐Engineered Temperature Coefficients

Advanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
Fiber Bragg gratings (FBGs) are intrinsically responsive to temperature and strain simultaneously. In this research, low‐loss FBGs with micro‐engineered temperature coefficients are fabricated, utilizing refractive index liquid‐filled microchannels in the cladding.
Zipei Song, Mohan Wang, Frank P. Payne, Patrick S. Salter, Tongyu Liu, Steve J. Elston, Martin J. Booth, Stephen M. Morris, Julian A. J. Fells   +8 more
wiley   +1 more source

BRCA1 alternative splicing in breast tumorogenesis [PDF]

Introduction: Alternative splicing helps transcription process to produce many proteins from single gene and has important roles on tumorogenesis. The BRCA1 gene has almost 11 alternate spliced variants which have been mentioned as susceptibility ...
اخوان, هما, اصغراوا, طاهیرا, حسینی اصل, سید سعید, فغانی, نفیسه, مهدی پور, پروین, وثوقی, ابراهیم, پیری دوگاهه, هادی   +6 more
core  

Identification of an Alternative Exon in a GABA Receptor Gene [PDF]

, 2018
The central dogma of biology states that DNA is transcribed into mRNA, which is then translated into proteins. In order for translation to occur, pre-mRNAs first must be processed.
Apgar, Shannon, Toro, Cecilia P.
core   +1 more source

Changes of the Alternative Splicing Variants of Human Telomerase Reverse Transcriptase during Gastric Carcinogenesis [PDF]

, 2009
Jinheng Xu, Yuchuan Wang, Xin Geng, Yanyun Li, Weiming Zhang   +4 more
openalex   +1 more source

3D Microprinting of Structures with Lanthanide‐Based Fluorophores on Optical Fibers for Multiplexed Sensing

Advanced Optical Materials, EarlyView.
Incorporating lanthanide‐based fluorophores into commercial resists for femtosecond direct laser writing enables a novel platform for multiplexed sensing. Porous, periodic, and solid luminescent microstructures fabricated directly on optical fiber tips are presented.
Valese Aslani, Shaghayegh Baghapour, Stephen C. Warren‐Smith, Wenqi Zhang, Esmat Ebadati, Sally E. Plush, Alois M. Herkommer, Andrea Toulouse, Shahraam Afshar V.   +8 more
wiley   +1 more source