Results 1 to 10 of about 248,138 (311)

Deep-learning augmented RNA-seq analysis of transcript splicing

Nature Methods, 2019
Zijun Zhang, Zhicheng Pan, Samir Adhikari   +2 more
exaly  

Splicing and transcription touch base: co-transcriptional spliceosome assembly and function

Nature Reviews Molecular Cell Biology, 2017
Lydia Herzel, Tara Alpert, Karla M Neugebauer   +2 more
exaly  

Nuclearly Encoded Splicing Factors Implicated in RNA Splicing in Higher Plant Organelles

Molecular Plant, 2010
Andéol Falcon De Longevialle, Ian Small, Claire Lurin   +2 more
exaly  

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

Proceedings of the National Academy of Sciences of the United States of America, 2014
Shihao Shen, Juw Won Park, Zhi-Xiang Lu   +2 more
exaly  

Defective control of pre–messenger RNA splicing in human disease

Journal of Cell Biology, 2016
Benoit Chabot, Lulzim Shkreta, Chabot Benoit   +2 more
exaly  

The regulation and function of post-transcriptional RNA splicing

Nature Reviews Genetics
L Stirling Churchman, Karine Choquet, Inés L Patop   +2 more
exaly  

TET dioxygenases localize at splicing speckles and promote RNA splicing [PDF]

Nucleus
The dynamic regulation of RNA metabolism plays a crucial part in cellular function, with emerging evidence suggesting an important role for RNA modifications in this process.
Florian D. Hastert, Jasmin Weber, Christina Bauer, Andreas Zhadan, Deepanshu N. D. Singh, Thomas C. Dix, Roland Arnold, Sergey Bessonov, Matthias Soller, Heinrich Leonhardt, M. Cristina Cardoso, Maria Arroyo   +11 more
doaj   +2 more sources

Dysregulation of RNA Splicing in Tauopathies [PDF]

Cell Reports, 2019
Summary: Pathological aggregation of RNA binding proteins (RBPs) is associated with dysregulation of RNA splicing in PS19 P301S tau transgenic mice and in Alzheimer’s disease brain tissues. The dysregulated splicing particularly affects genes involved in
Daniel J. Apicco, Cheng Zhang, Brandon Maziuk, Lulu Jiang, Heather I. Ballance, Samantha Boudeau, Choong Ung, Hu Li, Benjamin Wolozin   +8 more
doaj   +3 more sources

The potential impact of RNA splicing abnormalities on immune regulation in endometrial cancer [PDF]

Cell Death and Disease
RNA splicing controls the post-transcriptional level of gene expression, allowing for the synthesis of many transcripts with various configurations and roles.
Minyue Cao, Jiayu Yan, Yan Ding, Yiqin Zhang, Yihan Sun, Genyi Jiang, Yanli Zhang, Bilan Li   +7 more
doaj   +2 more sources

Long-read RNA-seq demarcates cis- and trans-directed alternative RNA splicing [PDF]

Nature Communications
Genetic regulation of alternative splicing constitutes an important link between genetic variation and disease. Nonetheless, RNA splicing is regulated by both cis-acting elements and trans-acting splicing factors.
Giovanni Quinones-Valdez, Kofi Amoah, Xinshu Xiao   +2 more
doaj   +2 more sources