Results 311 to 320 of about 326,335 (355)

Influence of ATXN2 intermediate CAG repeats, 9bp duplication and alternative splicing on SCA3 pathogenesis. [PDF]

Acta Neuropathol Commun
Lauerer M, Faber J, Casadei N, Santana MM, Auburger G, Pogoda M, Admard J, Kaupp L, Kos PL, Raposo M, Lima M, de Almeida LP, Garcia-Moreno H, Giunti P, de Vries J, van de Warrenburg BP, van Gaalen J, Grobe-Einsler M, Koyak B, Reetz K, Erdlenbruch F, Jacobi H, Infante J, Hengel H, Schöls L, Klockgether T, Rieß O, Hübener-Schmid J, ESMI study group.   +28 more
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RBM10 suppresses colorectal cancer invasion by regulating LncRNA SNHG17 alternative splicing. [PDF]

Sci Rep
An L, Chen P, He M, Li H, Zhou Y, Zhao H, Geng C.   +6 more
europepmc   +1 more source

Transition of CELF2 PAS usage promotes recovery of refractory JDM through alternative splicing regulation of CTSB. [PDF]

Mol Ther Nucleic Acids
Wei J, Zhang D, Lu X, Zhang K, Liu R, Wu X, Zhu J, Lai J, Su G, Wang L.   +9 more
europepmc   +1 more source

The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking. [PDF]

J Biol Chem
Couch T, McCullock TW, MacLean DM.
europepmc   +1 more source

KPNA2 promotes osteosarcoma progression by regulating the alternative splicing of DDX3X mediated by YBX1. [PDF]

Oncogene
Cao L, Jia K, Van Tine BA, Yu Y, Peng Y, Chen X, Pan Q, Yang W, Zhang Z, Shao Z, Wu W.   +10 more
europepmc   +1 more source

Alternative splicing broadens antiviral diversity at the humanOAS2locus

Davies EL, Sowar H, Balci A, Moorhouse E, Wickenhagen A, Turnbull ML, Palmarini M, Wilson SJ, Fletcher AJ.   +8 more
europepmc   +1 more source

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The physiology of alternative splicing

Nature Reviews Molecular Cell Biology, 2022
Alternative splicing is a substantial contributor to the high complexity of transcriptomes of multicellular eukaryotes. In this Review, we discuss the accumulated evidence that most of this complexity is reflected at the protein level and fundamentally shapes the physiology and pathology of organisms.
Luciano E. Marasco, Alberto R. Kornblihtt   +1 more
openaire   +3 more sources

Function of alternative splicing [PDF]

Gene, 2005
Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from the surprisingly low number of human genes. Unlike promoter activity, which primarily regulates the amount of transcripts, alternative splicing changes the structure of transcripts and their encoded proteins.
Shani Ben-Ari, Ilona Rafalska, Yesheng Tang, Zhaiyi Zhang, Hermona Soreq, Thangavel Alphonse Thanaraj, Stefan Stamm, Debra Toiber   +7 more
openaire   +2 more sources