Results 311 to 320 of about 411,790 (378)

The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8. [PDF]

Cell Biosci
Yang Y, Li Z, Yang Y, Xiao P, He Z, Zhang Z, Li Y, Shi L, Wang X, Tao Y, Fan J, Zhang F, Yang C, Yao F, Ji T, Zhang Y, Zhou B, Yu J, Guo A, Wei Z, Jiao W, Wu Y, Li Y, Wu D, Wu Y, Gao L, Hu Y, Pan J, Hu S, Yang X.   +29 more
europepmc   +1 more source

Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47

Cancer Communications, EarlyView.
Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang, Chen Zhang, Ruichen Zang, Weiwu Chen, Yining Guo, Haofei Jiang, Jing Le, Kunyu Wang, Haobo Fan, Xudong Wang, Sisi Mo, Peng Gao, Wenhao Guo, Xinrong Jiang, Fengbin Gao, Junming Jiang, Juyan Zheng, Yuxing Chen, Yicheng Chen, Yanlan Yu, Guoqing Ding   +20 more
wiley   +1 more source

NUMB alternative splicing and isoform-specific functions in development and disease. [PDF]

J Biol Chem
Dho SE, Othman K, Zhang Y, McGlade CJ.
europepmc   +1 more source

Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants

Chemistry &Biodiversity, EarlyView.
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Christiana Eleojo Aruwa, Saheed Sabiu
wiley   +1 more source

Alternative Splicing in the Heart: The Therapeutic Potential of Regulating the Regulators. [PDF]

Int J Mol Sci
Briganti F, Wang Z.
europepmc   +1 more source

In Situ Characterization of Competitive (De)Lithiation in Silicon/Graphite Composite Electrodes via Electrode Curvature Measurement

ChemElectroChem, Volume 12, Issue 6, March 15, 2025.
An in‐situ method for characterizing competitive (de)lithiation in silicon/graphite electrodes is developed in this paper. By utilizing electrode curvature measurements and establishing the curvature capacity relationship, the capacity evolution of individual components is quantified. Distinct competitive (de)lithiation stages are revealed. This method
Min Li, Huibing Liu, Yicheng Song, Bo Lu, Junqian Zhang   +4 more
wiley   +1 more source

Repurposing alternative splicing events as potential targets for the design of diagnostic and therapeutic tools in PCa. [PDF]

Front Oncol
Martínez-Montiel N, Vite-Arciniega JJ, Rosas-Murrieta NH, Martínez-Contreras RD.   +3 more
europepmc   +1 more source

Label‐Free Photonic Biosensors: Key Technologies for Precision Diagnostics

ChemistryEurope, EarlyView.
Photonic biosensors are versatile technologies promising unique advantages to improve current diagnosis workflows. On‐going research is directed to systems integration and automation as well as enhancing assay performance. Advances in bioengineering, material sciences, and photonics engineering will be the key toward their eventual implementation as ...
Maria Soler, Laura M. Lechuga
wiley   +1 more source

Alternative splicing induces sample-level variation in gene-gene correlations. [PDF]

BMC Genomics
Lu Y, Pierce BL, Wang P, Yang F, Chen LS.   +4 more
europepmc   +1 more source