Results 121 to 130 of about 513,952 (259)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Complementary and alternative therapies for osteoarthritis

Indian Journal of Rheumatology, 2006
R Handa, A Goel
doaj   +1 more source

Understanding the Effect of Propolis and Its Derivatives Against <i>Candida</i> Biofilm: New Approaches in the Search for Alternative Therapies. [PDF]

J Fungi (Basel)
Rivera-Yañez N, Hernández-Sánchez KM, Hernández-Rosas NA, Francisco-Cruz L, Nieto-Yañez O, Barrera-Ortega CC, Pozo-Molina G, Méndez-Catalá CF, Méndez-Cruz AR, Ruiz-Hurtado PA, Rivera-Yañez CR.   +10 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Newly isolated <i>Pakpunavirus</i>: efficacy and safety assessment in light of alternative therapies against <i>P. aeruginosa</i> skin infections. [PDF]

Front Microbiol
Necel A, Stasiłojć M, Wesołowski W, Narajczyk M, Kosznik-Kwaśnicka K, Kaźmierczak N, Naumiuk Ł, Loika H, Piechowicz L, Żywicka A.   +9 more
europepmc   +1 more source

Methicillin-Resistant Staphylococcus aurous: Epidemiology, Transmission and New Alternative Therapies: A Narrative Review. [PDF]

Iran J Public Health, 2023
Bouali N, Haddaji N, Hamadou WS, Ghorbel M, Bechambi O, Mahdhi A, Snoussi M.   +6 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Combined Complementary and Alternative Therapies for the Management of a Breech Fetus: A Feasibility Study. [PDF]

AJP Rep
Babbar S, Williams KB, Vawter L.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source