Results 151 to 160 of about 877,869 (275)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Complementary and alternative therapies for osteoarthritis

Indian Journal of Rheumatology, 2006
R Handa, A Goel
doaj   +1 more source

Combined Complementary and Alternative Therapies for the Management of a Breech Fetus: A Feasibility Study. [PDF]

AJP Rep
Babbar S, Williams KB, Vawter L.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Nível de conhecimentos sobre Leishmaniose Tegumentar Americana (LTA) e uso de terapias alternativas por populações de uma área endêmica da Amazônia do Maranhão, Brasil

Cadernos de Saúde Pública
Realizou-se estudo visando identificar e comparar que conhecimentos básicos e uso de terapias alternativas relativos à Leishmaniose Tegumentar Americana (LTA), têm populações residentes em cinco áreas rurais (Sexta Vicinal, Quinta Vicinal, Trilha 410 ...
Rosilene da Conceição R. Moreira, José Manuel Macário Rebêlo, Mônica Elinor Alves Gama, Jackson Maurício L. Costa   +3 more
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Organoid-based two-step drug screening for rapid identification of chemotherapy-resistant oesophageal squamous cell carcinoma and alternative therapies. [PDF]

Clin Transl Med
Shao CY, Ju S, Tong X, Hu K, Li Y, Zhu YX, Yang J, Li C, Xie YF, Cui Y, Deng WJ, Ding C, Qin SB, Zhao J.   +13 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Response to corticosteroids and alternative therapies in sarcoidosis-related hypercalcemia: A guideline-lacking retrospective analysis. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Robinson D, Crumpler D, Zhai G, Barney J.   +3 more
europepmc   +1 more source

Trends in the Use of Complementary and Alternative Therapies among US Adults with Current Asthma. [PDF]

Epidemiologia (Basel), 2023
Ogbu CE, Oparanma C, Ogbu SC, Ujah OI, Okoli ML, Kirby RS.   +5 more
europepmc   +1 more source