Results 171 to 180 of about 895,737 (304)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Response to corticosteroids and alternative therapies in sarcoidosis-related hypercalcemia: A guideline-lacking retrospective analysis. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Robinson D, Crumpler D, Zhai G, Barney J.   +3 more
europepmc   +1 more source

Bibliometric trend analysis of non-conventional (alternative) therapies in veterinary research. [PDF]

Vet Q, 2022
Domingues K, Franco NH, Rodrigues I, Stilwell G, Magalhães-Sant'Ana M.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Beyond Antivirals: Alternative Therapies for Long COVID. [PDF]

Viruses
Livieratos A, Gogos C, Akinosoglou K.
europepmc   +1 more source

Complementary and alternative therapies in skin cancer a literature review of biologically active compounds. [PDF]

Dermatol Ther, 2022
Hidalgo L, Saldías-Fuentes C, Carrasco K, Halpern AC, Mao JJ, Navarrete-Dechent C.   +5 more
europepmc   +1 more source

Calming the mind, healing the body: can alternative therapies help college students improve their health? [PDF]

, 2009
Gamtso, Carolyn B.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Antibiotic-Resistant <i>Pseudomonas aeruginosa</i>: Current Challenges and Emerging Alternative Therapies. [PDF]

Microorganisms
Hu M, Chua SL.
europepmc   +1 more source

Alternative therapies for dry eye disease. [PDF]

Curr Opin Ophthalmol, 2021
Mittal R, Patel S, Galor A.
europepmc   +1 more source