Results 171 to 180 of about 890,618 (298)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Powerful large scale inference in high dimensional mediation analysis. [PDF]
Roy A, Zhang X.
europepmc +1 more source
Behavior Change through Innovation Adoption: A Case Study of Alternative Mobility Solutions
Tatyana Chuzhanova
openalex +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Optimal selection of a metro tunnel excavation method using AHP and TOPSIS: a case study of Tehran metro. [PDF]
Rostami A +3 more
europepmc +1 more source
Communicating the Safety Benefits of Alternative Intersections
M C Holowaty
openalex +1 more source
Plant based Milk (Millet Milk) as a Vegan Alternative to Bovine Milk: A Comprehensive Review [PDF]
Kishor Kashinathrao Anerao +6 more
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Alternatives to incarceration for parents: a scoping review protocol. [PDF]
Charles P, Buck J, Harty J.
europepmc +1 more source

